Evidence map›Paper›PMID 42646918›Full record

ArticleTomography (Ann Arbor, Mich.)2026

High-Resolution 3T Intracranial Vessel Wall MRI in Patients Evaluated for Suspected Inflammatory Intracranial Vasculopathy: Morphologic and Follow-Up Findings from a Retrospective Case Series.

Yeliz Basar, Mujgan Orman, Tugce Ozdemir Gultekin, Ercan Karaarslan, Civan Islak

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Article in Tomography (Ann Arbor, Mich.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yeliz BasarDepartment of Radiology, Acibadem Healthcare Group, 34457 Istanbul, Turkey.ORCID 0000-0002-1321-3617
Mujgan OrmanDepartment of Radiology, Acibadem Healthcare Group, 34457 Istanbul, Turkey.ORCID 0000-0002-9629-0211
Tugce Ozdemir GultekinDepartment of Neurology, Acibadem Healthcare Group, 34457 Istanbul, Turkey.ORCID 0000-0003-4650-2965
Ercan KaraarslanDepartment of Radiology, School of Medicine, Mehmet Ali Aydinlar Acibadem University, 34638 Istanbul, Turkey.
Civan IslakDepartment of Radiology, Acibadem Healthcare Group, 34457 Istanbul, Turkey.ORCID 0000-0002-3626-6244

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur objective was to describe morphologic features and longitudinal changes observed on high-resolution vessel wall imaging (HR-VWI) in a selected retrospective case series of patients evaluated for suspected inflammatory intracranial vasculopathy.

methodsThis retrospective case series included patients who underwent 3T intracranial HR-VWI for suspected inflammatory intracranial vasculopathy. Clinical and imaging data were collected from medical records and imaging archives. Three radiologists reviewed baseline and follow-up examinations for vessel wall enhancement (VWE) pattern and grade, wall thickness, luminal narrowing, arterial distribution, diffusion-restricted lesions, and susceptibility-sensitive findings. Analyses were descriptive and patient-level. Each patient contributed one baseline and one final examination to longitudinal summaries; intermediate scans characterized individual trajectories only.

resultsNineteen patients were included, and 17 underwent serial HR-VWI. Median age was 46 years (IQR, 35.5-60.0 years), and 11 patients were female. Follow-up HR-VWI was available in 17 patients over a median of 391 days (IQR, 237-1819 days; range, 15-4034 days). VWE was present in all patients, with a purely concentric pattern in 15/19 (78.9%). The middle cerebral and internal carotid arteries were involved in 17/19 and 13/19 patients, respectively. Among the 17 patients with paired examinations, VWE grade decreased in 13 patients (76.5%) and remained stable in four patients (23.5%), with the median decreasing from 3.0 to 1.0. Maximum wall thickness decreased in 16 patients and remained stable in one, with the median changing from 2.0 mm to 1.4 mm.

conclusionsIn this selected retrospective case series of patients evaluated for suspected inflammatory intracranial vasculopathy, 3T HR-VWI commonly demonstrated concentric VWE and provided descriptive longitudinal information regarding enhancement evolution. These findings should not be interpreted as evidence of diagnostic performance.

Indexed as

Magnetic Resonance AngiographyMagnetic Resonance ImagingVasculitis, Central Nervous SystemAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective Studiescentral nervous system vasculitisintracranial vasculopathyprimary angiitis of the central nervous systemvessel wall imaging

Identifiers

PMID42646918
PMCPMC13517854

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