Evidence map›Paper›PMID 42646914›Full record

ArticleTomography (Ann Arbor, Mich.)2026

Factors Affecting Temporal Changes in Ablated Liver Volume After Radiofrequency Ablation for Hepatocellular Carcinoma Evaluated by Three-Dimensional Volumetric Computed Tomography.

Mayumi Higashi, Masahiro Tanabe, Yuna Fujii, Haruki Furutani, Jo Ishii, Yuto Takemura, Norikazu Tanabe, Issei Saeki, Taro Takami, Katsuyoshi Ito

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mayumi HigashiDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0000-0003-3929-9495
Masahiro TanabeDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0000-0002-0302-4257
Yuna FujiiDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.
Haruki FurutaniDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.
Jo IshiiDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0009-0009-7027-7869
Yuto TakemuraDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.
Norikazu TanabeDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0009-0005-9502-8886
Issei SaekiDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0000-0001-5885-5042
Taro TakamiDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0000-0002-6689-4989
Katsuyoshi ItoDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Yamaguchi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate associations between shrinkage of ablated liver area on computed tomography (CT) over time after radiofrequency ablation (RFA) and clinical parameters related to liver function and fibrosis.

methodsPatients with hepatocellular carcinoma who underwent RFA and follow-up CT were retrospectively reviewed. The ablated area volume (AAV) on CT obtained within 1 week and around 6 months after RFA was measured, and reduction rate of AAV was calculated. The AAV reduction rate was compared among Child-Pugh classification, modified albumin-bilirubin (mALBI) grades, FIB-4 index categories, and lesion locations using generalized estimating equations (GEE). Univariable and multivariable GEE analyses were performed to evaluate associations between the AAV reduction rate and clinical parameters.

resultsFifty-three lesions in 41 patients (median age, 76 [range, 38-88] years, 24 men) were evaluated. The AAV reduction rate was significantly lower in Child-Pugh class B than class A (

conclusionsThe AAV reduction rate tended to be lower in patients with impaired liver function and advanced liver fibrosis.

Indexed as

Carcinoma, HepatocellularCatheter AblationCone-Beam Computed TomographyImaging, Three-DimensionalLiverLiver NeoplasmsRadiofrequency AblationAdultAgedAged, 80 and overFemaleHumansLiver CirrhosisMaleMiddle AgedRetrospective Studiescomputed tomographyliverliver fibrosisliver functionradiofrequency ablation

Identifiers

PMID42646914
PMCPMC13517820

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.