ArticleSports (Basel, Switzerland)2026
Effects of High-Intensity Interval Training and Moderate-Intensity Continuous Training on Insulin Resistance Markers in Overweight and Obese Moroccan Adolescents.
Article in Sports (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Previous studies have shown that physical activity (PA) can improve insulin sensitivity and reduce insulin resistance (IR), a key determinant of metabolic dysfunction. While the beneficial effects of PA are well-documented in adults, evidence regarding the relationship between PA intensity and insulin resistance in adolescents, particularly in North African populations, remains scarce. This study aimed to compare the effects of a 12-week school-based high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) intervention, versus usual physical education, on insulin resistance as assessed by the homeostasis model assessment of insulin resistance (HOMA-IR) in overweight and obese non-diabetic Moroccan adolescents. The study included 90 non-diabetic overweight and obese Moroccan adolescents aged 12 to 17 years. Participants were randomly assigned to three groups (HIIT, MICT, and control) within a 12-week school-based intervention. Insulin resistance was assessed using the HOMA-IR index. Linear regression models were used to examine the associations between exercise modality and HOMA-IR, adjusting for age, sex, baseline body mass index (BMI), and baseline HOMA-IR. Compared with the control group, both HIIT and MICT were associated with significant reductions in HOMA-IR. In the fully adjusted models, HIIT showed a greater decrease of -0.90 (95% CI: -1.07 to -0.72) (all
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