Evidence map›Paper›PMID 42646807›Full record

ArticleTropical medicine and infectious disease2026

Socio-Demographic Factors Associated with Alcohol and Tobacco Use Among Virally Suppressed People Living with HIV in the Eastern Cape, South Africa.

Zanele Bennedict Nomatshila, Guillermo Alfredo Pulido Estrada, Sibusiso Cyprian Nomatshila, Teke Ruffin Apalata

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Article in Tropical medicine and infectious disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Zanele Bennedict NomatshilaSchool of Public Health, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha 5117, South Africa.
Guillermo Alfredo Pulido EstradaSchool of Public Health, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha 5117, South Africa.ORCID 0000-0001-6485-2059
Sibusiso Cyprian NomatshilaSchool of Public Health, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha 5117, South Africa.
Teke Ruffin ApalataFaculty of Health Sciences, University of Stirling, Stirling FK9 4LA, UK.ORCID 0000-0002-1329-3864

Funding

South African Medical Research Council MRC-RFACC 01-2014
6 · The paper itself

Abstract

backgroundAlcohol and tobacco use remain important public health concerns among people living with HIV (PLWH), even after achieving viral load suppression. This study examined the socio-demographic factors associated with alcohol and tobacco use among virally suppressed PLWH in the Eastern Cape Province, South Africa.

methodsA cross-sectional study was conducted among 244 adults receiving antiretroviral therapy with suppressed viral loads at public healthcare facilities in the Eastern Cape Province. Data were collected using the Alcohol Use Disorders Identification Test (AUDIT) and the WHO STEPwise questionnaire. Alcohol use was classified according to the AUDIT, and participants were further categorised into low-risk (AUDIT score < 8) and risky drinking (AUDIT score ≥ 8) for regression analyses. Associations between socio-demographic characteristics and alcohol use were initially examined using cross-tabulations and exact tests where appropriate. Univariable and multivariable binary logistic regression analyses were subsequently performed to identify factors independently associated with risky alcohol use and smoking. Adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were reported, with statistical significance set at

resultsOf the 244 participants, 57.0% were female, and 61.5% were employed. Based on the total AUDIT score, 60.2% of participants were classified as risky drinkers, while 44.3% were current smokers. In the multivariable analysis, employment was independently associated with risky alcohol use (AOR = 2.03, 95% CI: 1.11-3.73) and current smoking (AOR = 3.75, 95% CI: 1.98-7.08). Compared with single participants, married (AOR = 2.61, 95% CI: 1.25-5.45), separated (AOR = 5.19, 95% CI: 1.98-13.60), and divorced participants (AOR = 3.32, 95% CI: 1.05-10.49) had higher odds of risky alcohol use.

conclusionAlcohol use and tobacco smoking remain common among virally suppressed PLWH in the Eastern Cape Province. Although viral load suppression is an important treatment outcome, it does not fully reflect broader health behaviours that may compromise long-term health. Integrating routine screening for alcohol and tobacco use, together with targeted behavioural interventions and harm reduction strategies, into comprehensive HIV care may improve long-term health outcomes.

Indexed as

alcoholantiretroviral therapyhealth behaviourHIVquality of lifetobacco smokingviral load suppression

Identifiers

PMID42646807
PMCPMC13517806

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.