Evidence map›Paper›PMID 42646801›Full record

ArticleTropical medicine and infectious disease2026

Exploiting the Property of a New Series of 1,2,3-Triazole Compounds as Inhibitors of In Vivo and In Vitro Toxic Effects Caused by

Aldo Rodrigues da Silva, Ana Cláudia Rodrigues da Silva, Eladio Flores Sanchez, Gabriel Alves Souto de Aquino, Vitor Francisco Ferreira, Sabrina Baptista Ferreira, André Lopes Fuly

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aldo Rodrigues da SilvaInstituto de Biologia, Universidade Federal Fluminense, Niterói 24020-141, RJ, Brazil.
Ana Cláudia Rodrigues da SilvaInstituto de Biologia, Universidade Federal Fluminense, Niterói 24020-141, RJ, Brazil.
Eladio Flores SanchezFundação Ezequiel Dias, Belo Horizonte 30510-010, MG, Brazil.
Gabriel Alves Souto de AquinoDepartamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21949-900, RJ, Brazil.ORCID 0000-0002-5010-2852
Vitor Francisco FerreiraFaculdade de Farmácia, Laboratório Inovação em Química e Tecnologia Farmacêutica, Universidade Federal Fluminense, Niterói 24220-900, RJ, Brazil.ORCID 0000-0002-2166-766X
Sabrina Baptista FerreiraDepartamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21949-900, RJ, Brazil.ORCID 0000-0002-5363-0888
André Lopes FulyInstituto de Biologia, Universidade Federal Fluminense, Niterói 24020-141, RJ, Brazil.ORCID 0000-0002-5265-5258

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304243/2024-8Conselho Nacional de Desenvolvimento Científico e Tecnológico 311447/2022-8Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010/00168/2015Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/01.001918/2015Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.163/2014Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/203.954/2024Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01858-15
6 · The paper itself

Abstract

(1) Background: Snake bite envenomation is a neglected disease that affects impoverished and rural areas, causing deaths and physical sequelae. (2) Objective: A novel series of eight 1,2,3-triazole compounds, AM50, AM51, AM52, AM53, AM54, AM55, AM56, and AM57, were synthesized and assessed as inhibitors of toxic activities of

Indexed as

antivenomB. jararacussu snakeneglected diseasetreatmenttriazole scaffold

Identifiers

PMID42646801
PMCPMC13517514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.