Evidence map›Paper›PMID 42646766›Full record

ArticleToxins2026

Recombinant BaMtx Preserves the Biological Properties of a Lys49 Phospholipase A

Daniel Torrejón, Angie Regalado, Alex Proleón, Víctor Otárola, Fanny Lazo, Edith Rodríguez, Erasmo Colona-Vallejos, Libertad Alzamora-Gonzales, Jherson Cisneros-Gutierrez, Jacquelyne Zarria-Romero and 8 more

Abstract read
In one paragraph

Article in Toxins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Daniel TorrejónGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0001-9385-6921
Angie RegaladoGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0002-9726-6686
Alex ProleónGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0001-7883-3916
Víctor OtárolaGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.
Fanny LazoGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0003-2634-1631
Edith RodríguezGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0001-6870-9778
Erasmo Colona-VallejosMODULANS Research Group, Faculty of Biological Sciences, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru.ORCID 0000-0001-9759-288X
Libertad Alzamora-GonzalesMODULANS Research Group, Faculty of Biological Sciences, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru.ORCID 0000-0002-7425-7453
Jherson Cisneros-GutierrezMODULANS Research Group, Faculty of Biological Sciences, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru.ORCID 0009-0008-6407-5235
Jacquelyne Zarria-RomeroGrupo de Investigación de Reproducción, Biología del Desarrollo y Ecotoxicología (BIOTOXIC), Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra 34 S/N, Ciudad Universitaria, Lima 15081, Peru.
Miryam Paola Alvarez FloresCentre of Excellence in New Target Discovery (CENTD), Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0002-7986-923X
Renata Nascimento GomesCentre of Excellence in New Target Discovery (CENTD), Butantan Institute, São Paulo 05503-900, Brazil.
Thatiana Corrêa de MeloCentre of Excellence in New Target Discovery (CENTD), Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0001-7002-5180
Ronnie G GavilanCentro Nacional de Salud Pública, Instituto Nacional de Salud-Perú, Lima 15072, Peru.ORCID 0000-0003-1437-5607
Javier Cárdenas TenorioLaboratorio de Bioquímica, Facultad de Ciencias de la Salud, Universidad Nacional del Callao, Av. Juan Pablo ΙΙ 306, Callao 07011, Peru.ORCID 0000-0002-6112-2584
Félix A UrraLaboratorio de Plasticidad Metabólica y Bioenergética, Núcleo Interdisciplinario de Farmacología e Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0001-8582-4399
Dan E Vivas-RuizGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0003-4417-2026
Armando YarlequéGrupo de Investigación Toxinas de Origen Animal y sus Antivenenos (TOXIVEN), Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Av. Venezuela Cdra. 34 S/N, Ciudad Universitaria, Lima 15081, Peru.ORCID 0000-0002-8038-2162

Funding

National Council of Science, Technology and Technological Innovation PE501087970-2024-PROCIENCIANational University of San Marcos PCONFIGI N°B2210014PROCIENCIA PE501087970-2024-PROCIENCIASão Paulo Research Foundation 2015/50040-4, 2020/13139-0 and 2013/07467-1
6 · The paper itself

Abstract

Lys49 phospholipase A2 (Lys49-PLA

Indexed as

Antineoplastic AgentsBothrops atroxCrotalid VenomsPhospholipases A2AnimalsBothropsCell Line, TumorCell SurvivalFemaleHumansMiceMice, Inbred BALB CMuscle, SkeletalPichiaRecombinant ProteinsSaccharomycetalesAntineoplastic AgentsCrotalid VenomsPhospholipases A2Recombinant ProteinsBothrops atroxcancer cell linesLys49 PLA2 homologuePichia pastorisvenom

Identifiers

PMID42646766
PMCPMC13517361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.