Bacterial Chondronecrosis with Osteomyelitis (BCO) in Broiler Chickens: Bacterial Causes, Pathophysiology and Control, with a Focus on the Potential of Electron Beam-Inactivated Vaccines.

Udara Rathnayake, Ruvindu Perera, Palmy R R Jesudhasan, Adnan Alrubaye

Abstract readReview

In one paragraph

Review in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Udara RathnayakeCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0001-6784-6033

Ruvindu PereraCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0009-0006-3625-3589

Palmy R R JesudhasanPoultry Production and Product Safety Research Unit, United States Department of Agriculture-Agricultural Research Service, Fayetteville, AR 72701, USA.ORCID 0000-0001-9128-4544

Adnan AlrubayeCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0002-5122-9150

Funding

National Institute of Food and Agriculture 2024-67015-42629

6 · The paper itself

Abstract

Bacterial chondronecrosis with osteomyelitis (BCO) is a major cause of lameness in modern broiler chickens. It remains a persistent challenge in the broiler industry, resulting in substantial economic losses and serious animal health concerns. The pathogenesis of BCO involves rapid muscle growth, resulting in disproportionate body weight relative to skeletal maturity, thereby increasing mechanical stress and leading to microfractures and osteochondrotic clefts in the proximal growth plates of the femora and tibiae. Infection progresses via hematogenous dissemination and colonization of the leg bones by opportunistic pathogens, primarily

Indexed as

antimicrobial resistancebroiler welfarechondronecrosiseBeamlamenessosteomyelitisvaccine

Identifiers

PMID42646668

DOI10.3390/vaccines14080649

PMCPMC13517342

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.