Evidence map›Paper›PMID 42646666›Full record

ArticleVaccines2026

Preclinical Safety Evaluation of a Replication-Defective Canine Adenovirus Type 2 Vector-Based SARS-CoV-2 Vaccine Candidate in Murine Models.

Denis Omara, Christian Ndekezi, Susan Mugaba, Angella Nakyanzi, Fortunate Natwijuka, Anne Kapaata, Frank Kato, Drake Byamukama, David E Ggwaabya, Orla Mugulusi and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Denis OmaraUganda Virus Research Institute (UVRI), Entebbe P.O. Box 49, Uganda.ORCID 0000-0001-7936-1754
Christian NdekeziUganda Virus Research Institute (UVRI), Entebbe P.O. Box 49, Uganda.
Susan MugabaMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.
Angella NakyanziUganda Virus Research Institute (UVRI), Entebbe P.O. Box 49, Uganda.ORCID 0000-0003-2866-5998
Fortunate NatwijukaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala P.O. Box 7062, Uganda.
Anne KapaataMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.ORCID 0000-0002-0726-1276
Frank KatoMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.ORCID 0000-0001-5075-0756
Drake ByamukamaMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.
David E GgwaabyaMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.
Orla MugulusiMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.
Freddie BwangaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala P.O. Box 7062, Uganda.
David P KateteDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala P.O. Box 7062, Uganda.
Enock MatovuCentral Laboratory for Animal Research Facility (CLARF), College of Veterinary Medicine, Animal Resources and Biosecurity (COVAB), Makerere University, Kampala P.O. Box 7062, Uganda.
Joseph OloboDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala P.O. Box 7062, Uganda.
Ekii Andrew ObukuMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.
Obondo James SandeDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala P.O. Box 7062, Uganda.ORCID 0000-0002-2301-5980
Jennifer SerwangaMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.
Stephen CoseMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe P.O. Box 49, Uganda.ORCID 0000-0002-5156-037X
Pontiano KaleebuUganda Virus Research Institute (UVRI), Entebbe P.O. Box 49, Uganda.
Sheila N BalindaUganda Virus Research Institute (UVRI), Entebbe P.O. Box 49, Uganda.ORCID 0000-0001-8374-3122

Funding

Science, Technology and Innovation (STI) Secretariat through the Office of the President (OP) of Uganda https://sti.go.ug/
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

canine adenovirus type 2 (CAV-2) vectormouse modelpreclinical studysafetySARS-CoV-2vaccines

Identifiers

PMID42646666
PMCPMC13517468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.