Evidence map›Paper›PMID 42646657›Full record

ArticlePediatric reports2026

Assessment of Caries Risk Through Clinical and Salivary Parameters in Pediatric Patients with Cleft Lip and Palate.

Alícia Lima, Anabela Paula, Catarina Nunes, Raquel Travassos, Bárbara Oliveiros, Carlos Miguel Marto, Eunice Carrilho, Inês Francisco, Francisco Vale

Abstract read
In one paragraph

Article in Pediatric reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alícia LimaInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
Anabela PaulaInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.ORCID 0000-0001-6154-4173
Catarina NunesInstitute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
Raquel TravassosInstitute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.ORCID 0000-0001-8937-361X
Bárbara OliveirosLaboratory of Evidence-Based and Precision Dentistry, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal.ORCID 0000-0001-7836-8161
Carlos Miguel MartoInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.ORCID 0000-0001-9269-5417
Eunice CarrilhoInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.ORCID 0000-0002-5759-5557
Inês FranciscoInstitute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.ORCID 0000-0002-3283-5104
Francisco ValeInstitute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.ORCID 0000-0003-2615-2929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study is to assess caries-related indicators (DMFT and ICDAS indices), plaque index, salivary pH and buffering capacity, and dietary and oral hygiene habits in patients with cleft lip and/or palate undergoing orthodontic treatment, compared with a control group of healthy patients.

methodsThis pilot case-control study included 26 patients undergoing orthodontic treatment, 13 patients with cleft lip and/or palate and 13 healthy individuals. The following variables were assessed: diet and oral hygiene through a questionnaire; salivary pH and buffering capacity; caries risk, using the DMFT and ICDAS indices; and plaque index, using the ImageJ Software.

resultsNo statistically significant differences were detected in the DMFT index, salivary pH, and plaque index; nor in the diet, oral hygiene and salivary buffering capacity. A slightly higher plaque index was observed in patients with cleft lip and/or palate compared to healthy patients. There was a statistically significant difference in the location of plaque, with a higher incidence in the upper central incisors in the study group.

conclusionThis pilot study suggests no statistically significant differences in the DMFT index, plaque index, salivary pH, and buffering capacity between patients with cleft lip and/or palate and healthy controls undergoing orthodontic treatment. However, a higher incidence of bacterial plaque on the upper central incisors was observed in patients with cleft lip and/or palate.

Indexed as

cleft lipcleft lip and palatecleft palatedental cariesDMFT indexorthodontics

Identifiers

PMID42646657
PMCPMC13516454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.