Evidence map›Paper›PMID 42646638›Full record

ArticleMedical sciences (Basel, Switzerland)2026

Orthopaedic Trauma in Patients with Documented Alcohol Use: Injury Mechanisms, Clinical Characteristics, and Geriatric Vulnerability.

Irina Sirbu, Bianca-Ana Dmour, Stefan-Dragos Tîrnovanu, Bogdan Puha, Eliza-Geanina Cogian, Mariana Zubenschi, Alexandru Filip, Ioana-Dana Alexa, Mihaela-Camelia Tîrnovanu, Popescu Dragos-Cristian and 2 more

Abstract read
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Irina SirbuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Bianca-Ana DmourGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Stefan-Dragos TîrnovanuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Bogdan PuhaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-9814-7742
Eliza-Geanina Cogian"Ion Creangă" State Pedagogical University of Chișinău, 1 Ion Creangă Street, MD-2069 Chișinău, Moldova.
Mariana Zubenschi"Ion Creangă" State Pedagogical University of Chișinău, 1 Ion Creangă Street, MD-2069 Chișinău, Moldova.ORCID 0000-0002-4890-2068
Alexandru FilipGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Ioana-Dana AlexaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Mihaela-Camelia TîrnovanuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Popescu Dragos-CristianGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Adrian-Claudiu CarpGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-5300-8426
Awad DmourGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0005-1154-7145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol-related conditions may influence both injury patterns and in-hospital management in orthopaedic trauma. This study evaluated the clinical characteristics, injury mechanisms, treatment patterns, and hospital outcomes of adults with acute orthopaedic trauma and documented alcohol use, with particular attention to geriatric vulnerability and alcohol withdrawal.

methodsThis retrospective single-centre cohort included adults admitted between January 2018 and December 2025 with acute musculoskeletal trauma and an alcohol-related diagnosis during the same hospitalisation. Patients were classified according to their predominant recorded alcohol-related presentation. Geriatric patients, defined as those aged 65 years or older, were compared with younger adults. Injury mechanisms, comorbidities, operative treatment, intensive care unit involvement, hospital length of stay, mortality, and recorded hospitalisation costs were analysed.

resultsThe final cohort comprised 294 patients, including 87 geriatric patients. Geriatric patients more frequently sustained same-level or low-energy falls than younger adults (46.0% versus 25.6%; Holm-adjusted

conclusionsOrthopaedic trauma patients with documented alcohol use represent a clinically heterogeneous population. Geriatric patients showed greater vulnerability to low-energy trauma, proximal femoral fracture, comorbidity, and intensive care involvement, while alcohol withdrawal identified patients with a more complex hospital course. Early recognition of withdrawal risk and enhanced inpatient safety measures may improve orthopaedic care. These findings support careful assessment of alcohol-related risk, early recognition of withdrawal, and heightened inpatient safety precautions.

Indexed as

Alcohol DrinkingWounds and InjuriesAccidental FallsAgedAged, 80 and overFemaleFractures, BoneHospitalizationHumansLength of StayMaleMiddle AgedRetrospective Studiesalcohol usealcohol withdrawalgeriatric traumahospital outcomesintensive carelow-energy fallsorthopaedic traumaproximal femoral fracture

Identifiers

PMID42646638
PMCPMC13515790

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.