Evidence map›Paper›PMID 42646626›Full record

ArticleMedical sciences (Basel, Switzerland)2026

Distinct Transcriptional Programs Controlled by

João Carlos Degraf Muzzi, Bonald Cavalcante Figueiredo, Jean Silva de Souza Resende, Igor Samesima Giner, Mauro Antônio Alves Castro, Enzo Lalli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João Carlos Degraf MuzziOncology Division, Instituto de Pesquisa e Faculdades Pelé Pequeno Príncipe, Curitiba 80250-060, PR, Brazil.
Bonald Cavalcante FigueiredoOncology Division, Instituto de Pesquisa e Faculdades Pelé Pequeno Príncipe, Curitiba 80250-060, PR, Brazil.ORCID 0000-0002-1051-2056
Jean Silva de Souza ResendeOncology Division, Instituto de Pesquisa e Faculdades Pelé Pequeno Príncipe, Curitiba 80250-060, PR, Brazil.ORCID 0000-0003-2209-790X
Igor Samesima GinerOncology Division, Instituto de Pesquisa e Faculdades Pelé Pequeno Príncipe, Curitiba 80250-060, PR, Brazil.ORCID 0000-0002-2397-4858
Mauro Antônio Alves CastroBioinformatics and Systems Biology Laboratory, Federal University of Paraná, Curitiba 81531-980, PR, Brazil.
Enzo LalliInstitut de Pharmacologie Moléculaire et Cellulaire CNRS UMR7275, Inserm U1323, Université Côte d'Azur, 06560 Valbonne, France.ORCID 0000-0002-0584-5681

Funding

Behring Foundation 25000.029124/2021-31CNRS IIPACT International Research NetworkConselho Nacional de Desenvolvimento Científico e Tecnológico
6 · The paper itself

Abstract

BACKGROUND/

objectivesAdrenocortical carcinoma (ACC) is a rare malignancy in which overexpression of steroidogenic factor-1 (SF-1/

methodsRegulatory network inference using RTN/ARACNe was applied to the TCGA-ACC cohort.

results

conclusionsThese findings indicate limited detectable global transcriptional convergence between

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical Carcinomabeta CateninSteroidogenic Factor 1Transcription, GeneticCell Line, TumorGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansWnt Signaling Pathwaybeta CateninNR5A1 protein, humanSteroidogenic Factor 1adrenocortical carcinomaLEF1NR5A1SF-1TCF7transcriptional regulatory networkβ-catenin

Identifiers

PMID42646626
PMCPMC13515156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.