Observational studyMedical sciences (Basel, Switzerland)2026
Consultation Lag and Early Improvement in Pediatric Daily Headache: A Retrospective Observational Study.
Observational study in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundPediatric daily headaches are refractory and disabling. However, the influence of the interval between daily headache onset and initial specialist consultation on clinical outcomes remains unknown.
methodsThis retrospective observational study included 51 children and adolescents presenting with daily headaches. Consultation lag was defined as the interval between the date when the headache first became daily and the initial consultation. The primary outcome was headache improvement (≥50% reduction in monthly headache days) at 3-4 months, and the secondary outcome was improvement at 6-7 months. Multivariate logistic regression and receiver operating characteristic curve analyses were performed.
resultsImprovements were observed in 41.2% of patients at 3-4 months and 60.0% at 6-7 months. Each additional week of consultation lag was associated with a 12% decrease in the odds of a 3-4-month improvement (adjusted odds ratio, 0.875; 95% confidence interval [CI], 0.783-0.979;
conclusionsA shorter consultation lag was independently associated with early improvement in pediatric daily headaches regardless of comorbidities. Patients presenting within this exploratory 5-week window were substantially more likely to improve early in this cohort; however, this threshold requires prospective external validation before it can inform clinical decision-making. These findings support consideration of prompt specialist referral following the onset of daily headache in children.
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