Evidence map›Paper›PMID 42646486›Full record

ReviewMarine drugs2026

Marine Food Polysaccharides: Representative Structural Features, Immunomodulatory Effects, and Food Applications.

Yunhan Li, Xinhong Wang, Xiang Li, Nan Wei, Dawei Jiang, Ming Li, Chong Yu, Juan Guo, Keqiang Li, Haifeng Wang and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yunhan LiDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xinhong WangDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiang LiDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Nan WeiDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Dawei JiangZhangzidao Group Co., Ltd., Dalian 116200, China.
Ming LiZhangzidao Group Co., Ltd., Dalian 116200, China.
Chong YuDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Juan GuoDalian Institute of Marine Traditional Chinese Medicine, Dalian 116622, China.
Keqiang LiDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Haifeng WangDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.ORCID 0000-0002-2344-1066
Ning LiDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.ORCID 0000-0002-6518-2541

Funding

Dalian Science and Technology Innovation Foundation on Key Basic Research Project 2025JJ11PT001Educational Department of Liaoning Province LJ212410163040
6 · The paper itself

Abstract

Marine food polysaccharides (MFPs) are structurally diverse biopolymers shaped by the marine environment, with emerging roles in immune regulation and food design. This review summarizes the representative structural features of MFPs, and evaluates their effects on innate and adaptive immune responses and associated signaling pathways. The influences of molecular weight, sulfation, branching, and monosaccharide composition on biological activity are also discussed. In addition, this review discusses the applications of MFPs in food additives, packaging, delivery systems, and functional foods. Despite growing evidence, challenges remain in resolving higher-order structures, understanding bidirectional immune effects and maintaining stability in complex matrices. Advancing integrated structural and food design approaches could enable the rational use of MFPs as next-generation functional ingredients.

Indexed as

Aquatic OrganismsImmunologic FactorsPolysaccharidesAnimalsFunctional FoodHumansImmunologic FactorsPolysaccharidesfunctional applicationsimmunomodulatory effectsmarine polysaccharidestructural features

Identifiers

PMID42646486
PMCPMC13514180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.