Evidence map›Paper›PMID 42646475›Full record

ArticleMarine drugs2026

Successful Combination of Ulvans and Thermal Spring Waters from as Burgas (Ourense) for Hydrating Cosmetic Creams in Healthy Volunteers.

Isa B D Ingrez, María Milagros Fernández-Varela, María Dolores Torres, Natalia Fariñas-Valiña, José Gantes, Manuela Buján, Antonio Muiños, Herminia Domínguez, María Reyes Pérez-Fernández

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Isa B D IngrezPorto-Muiños. S.L., Polígono Industrial O Acevedo, Parcela 14, Cerceda, 15185 A Coruña, Spain.
María Milagros Fernández-VarelaEscuela Universitaria de Enfemería, SERGAS, Ramón Puga 52-54, 32005 Ourense, Spain.ORCID 0000-0003-0633-352X
María Dolores TorresCINBIO, Department of Chemical Engineering, University of Vigo, Campus Ourense, 32004 Ourense, Spain.ORCID 0000-0001-6811-1290
Natalia Fariñas-ValiñaEscuela Universitaria de Enfemería, SERGAS, Ramón Puga 52-54, 32005 Ourense, Spain.ORCID 0009-0009-4511-8110
José GantesCosmeticos Anfer S.L., c/Parroquia de Bergondo, Parcela R-10, Shed 2, Bergondo Industrial Park, Bergondo, 15165 A Coruña, Spain.
Manuela BujánPorto-Muiños. S.L., Polígono Industrial O Acevedo, Parcela 14, Cerceda, 15185 A Coruña, Spain.
Antonio MuiñosPorto-Muiños. S.L., Polígono Industrial O Acevedo, Parcela 14, Cerceda, 15185 A Coruña, Spain.
Herminia DomínguezCINBIO, Department of Chemical Engineering, University of Vigo, Campus Ourense, 32004 Ourense, Spain.ORCID 0000-0002-6475-3242
María Reyes Pérez-FernándezEscuela Universitaria de Enfemería, SERGAS, Ramón Puga 52-54, 32005 Ourense, Spain.

Funding

Ministerio de Economía y Competitividad PID2021-124017-B-I00Xunta de Gaicia 14_IN606D_2023_2549021Xunta de Galicia GRC-ED431C 2022/08
6 · The paper itself

Abstract

Different hydrating cosmetic creams were formulated with ulvans obtained by a previously optimized process, consisting of hydrothermal treatment and a solvent-free concentration stage to obtain ulvans with 80% purity in carbohydrates, 34% rhamnose, 11% sulfate and >10 kDa. The incorporation of low-mineralization thermal spring waters in the formulation of hydrating creams with 1% ulvans and green ingredients caused a shear thinning behavior that was more marked than in creams formulated with distilled water. As Burgas thermal spring water caused the largest decay, suggesting an improvement in the cream's spreadability on the skin. This spring water was selected for formulating and bottling a commercial hydrating cream that was further evaluated regarding both physicochemical and biometric properties with a group of 120 healthy volunteers to assess the performance of both ulvans and As Burgas thermal spring water. The results of both objective and subjective evaluation indicate the enhanced skin hydration provided by ulvan and thermal spring water, as well as their favorable additive effect. A high tolerance was observed because all tested creams decreased the tightness sensation, and scaling was significantly reduced in the ulvan group. The findings confirm the potential additive skin benefits of combining ulvan with thermal spring water in hand cream formulations.

Indexed as

CosmeticsHot SpringsMineral WatersSkin CreamAdultFemaleHealthy VolunteersHumansMaleSkinWaterYoung AdultCosmeticsMineral WatersWatercolorcreamsfunctional and biometricrheologyulvan

Identifiers

PMID42646475
PMCPMC13514620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.