Evidence map›Paper›PMID 42646201›Full record

ReviewJournal of functional biomaterials2026

Comparative Analysis of Bone Remodeling Dynamics and Bone Vitality Following Standard Bone Augmentation Procedures: A Review.

Nikola Gapińska, Marek Śmielecki, Kornel Krasny

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nikola GapińskaDoctoral School of Quantitative and Natural Sciences, Maria Curie-Skłodowska University, Weteranów 18, 20-038 Lublin, Poland.ORCID 0000-0001-6784-2032
Marek ŚmieleckiCentrum Stomatologii Śmieleccy, Osiedle Władysława Łokietka 33, 62-200 Gniezno, Poland.
Kornel KrasnyMEDICARE Stomatologia sp. z o.o., Mireckiego 13a/11, 05-300 Mińsk Mazowiecki, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone augmentation procedures are widely used in implant dentistry to reconstruct deficient alveolar bone and support implant placement. However, outcomes are often evaluated mainly by defect filling, volumetric stability, or implant survival, which do not necessarily reflect the biological quality of regenerated tissue. This narrative review synthesizes human and supporting mechanistic evidence across autogenous, allogeneic, xenogeneic, and alloplastic grafts, including biologically functionalized constructs, with emphasis on bone remodeling dynamics and functional regeneration. Available evidence indicates that volumetric preservation alone should not be considered equivalent to complete bone regeneration and that remodeling is material-, product-, processing-, and indication-dependent. Augmented sites may contain newly formed vital bone together with persistent residual graft particles, forming a hybrid tissue whose significance depends on graft integration, vascularization, remodeling capacity, and the intended therapeutic objective. Persistent particles may influence the local immune microenvironment and, under unfavorable conditions, contribute to foreign body reactions or other complications, although such events appear uncommon and causal relationships remain uncertain. Biomaterial assessment should integrate quantitative, structural, and biological parameters, while residual graft persistence should be interpreted in an indication-specific manner rather than as evidence of treatment failure or inferior long-term performance in isolation.

Indexed as

allograftsalloplastic bone substitutesbiological functionalizationbone augmentationbone remodelingdental biomaterialshistomorphometryresidual graft materialvital bonexenografts

Identifiers

PMID42646201
PMCPMC13514292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.