Evidence map›Paper›PMID 42646114›Full record

ReviewJournal of fungi (Basel, Switzerland)2026

Fungal Hydrophobins: Taxonomic Distribution, Functional Roles, Physicochemical Properties, and Biotechnological Applications.

Sandra de Camargo Lameu, Matheus Henrique Galvão, Isabelle Teixeira Mello, Fabio Marcio Squina

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sandra de Camargo LameuLaboratory of Molecular Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares, km 92.5, Sorocaba 18023-000, São Paulo, Brazil.
Matheus Henrique GalvãoLaboratory of Molecular Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares, km 92.5, Sorocaba 18023-000, São Paulo, Brazil.ORCID 0009-0002-5473-3341
Isabelle Teixeira MelloLaboratory of Molecular Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares, km 92.5, Sorocaba 18023-000, São Paulo, Brazil.
Fabio Marcio SquinaLaboratory of Molecular Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares, km 92.5, Sorocaba 18023-000, São Paulo, Brazil.ORCID 0000-0002-8154-7459

Funding

The Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 306363/2025-9, 403844/2023-1The São Paulo Research Foundation (FAPESP) 26/00614-9, 23/12398-0, 22/05731-2, 20/05784-3, 22/08958-8, 2025/15191-3
6 · The paper itself

Abstract

Hydrophobins are small, cysteine-rich amphipathic proteins predominantly produced by filamentous fungi, known for their ability to self-assemble at hydrophobic-hydrophilic interfaces. These proteins are essential for fungal development, surface interactions, pathogenicity, and environmental adaptation, and they have attracted growing interest for biotechnological applications. In this work, we provide a narrative review of fungal hydrophobins, based on a systematic literature search and manual curation of eligible studies integrated with protein database records from Ascomycota and Basidiomycota. Information was compiled from peer-reviewed publications selected according to predefined eligibility criteria and complemented with UniProt records, covering taxonomic distribution, functional and biophysical properties, and physiological and pathogenic roles. Significant diversity in molecular features and physicochemical profiles was observed, indicating functional specialization across different ecological niches and lifestyles. Additionally, the compiled data highlight various biotechnological applications, such as surface modification, enzyme immobilization, drug delivery systems, biomaterial development, and environmentally sustainable technologies. By consolidating molecular, functional, and applied information across a wide range of fungal species, this review provides a comprehensive reference framework for hydrophobin research and biotechnological innovation.

Indexed as

amphipathic proteinsfilamentous fungihydrophobinsphysicochemical propertiessurface-active biomolecules

Identifiers

PMID42646114
PMCPMC13514795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.