Evidence map›Paper›PMID 42645873›Full record

ReviewJournal of cardiovascular development and disease2026

Evolution of Sac Filling Techniques and Concepts in Endovascular Treatment of Abdominal Aortic Aneurysm: A Narrative Review.

Linyao Zhu, Yuhang Zhou, Jichun Zhao, Ding Yuan, Tiehao Wang, Jiarong Wang, Chengxin Weng

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linyao ZhuDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.
Yuhang ZhouDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.
Jichun ZhaoDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.
Ding YuanDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.
Tiehao WangDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.ORCID 0000-0003-1607-3995
Jiarong WangDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.
Chengxin WengDivision of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, 37 Guo Xue Alley, Chengdu 610041, China.

Funding

Chengdu Science and Technology Bureau 2024-YF05-00194-SNNational Natural Science Foundation of China 82300542National Natural Science Foundation of China 82302152National Natural Science Foundation of China 82470501Science and Technology Department of Sichuan Province 2024YFFK0237Science and Technology Department of Sichuan Province 2024YFFK0238Science and Technology Department of Sichuan Province 2024YFHZ0065
6 · The paper itself

Abstract

Endovascular aortic aneurysm repair (EVAR) has become the first-line treatment for abdominal aortic aneurysms (AAA); however, its long-term durability is affected by Type II endoleak. This narrative review describes the evolution of sac filling techniques and concepts developed to address this complication. In selected cases of diagnosed Type II endoleaks, early therapeutic sac filling, while clinically indicated, is frequently constrained by difficult access, variable success rates, and recurrence. Consequently, prophylactic sac filling during primary EVAR has been adopted as an alternative approach, with reported high technical success and reduced endoleak incidence. The subsequent Nellix Endovascular Aneurysm Sealing (EVAS) system, although early results showed technical feasibility, was associated with graft migration, endobag separation, and reintervention at long-term follow-up, leading to its withdrawal from the market. Currently, devices based on shape memory polymer (SMP) provide early observations of decreased endoleaks and sac regression. This review outlines the transition from reactive management to preventive strategies, and, more recently, to patient-specific, material-based approaches, while showcasing emerging strategies that may influence long-term EVAR outcomes. However, these novel approaches remain under investigation, and larger controlled studies with extended follow-up are required to establish their clinical utility.

Indexed as

abdominal aortic aneurysmendovascular aortic aneurysm repairsac fillingshape memory polymertype II endoleak

Identifiers

PMID42645873
PMCPMC13513900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.