Evidence map›Paper›PMID 42645770›Full record

ArticleAnatomical science international2026

Disrupted myeloarchitecture accompanying anatomical abnormalities in the auditory pathway of reeler mice.

Fuduki Inoguchi, Amirlan Byambadash, Dai Ihara, Yu Katsuyama

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Article in Anatomical science international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fuduki InoguchiDivision of Neuroanatomy, Department of Anatomy, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Amirlan ByambadashDivision of Neuroanatomy, Department of Anatomy, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Dai IharaDivision of Neuroanatomy, Department of Anatomy, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Yu KatsuyamaDivision of Neuroanatomy, Department of Anatomy, Shiga University of Medical Science, Otsu, 520-2192, Japan. kats@belle.shiga-med.ac.jp.ORCID https://orcid.org/0000-0002-5758-9181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reelin plays a crucial role in neuronal migration and synaptic organization during brain development. Mice lacking Reelin (reeler mice) exhibit severe disorganization in cortical and cerebellar structures. Given that reeler mice show abnormal auditory brainstem responses, we investigated the cytoarchitecture and myeloarchitecture of major relay nuclei in the central auditory pathway. By Kluver-Barrera staining and Bielschowsky staining, we analyzed the primary auditory cortex, medial geniculate body, inferior colliculus, superior olivary nucleus, nucleus of the trapezoid body, and cochlear nucleus in reeler and wild-type mice. We observed marked structural abnormalities across multiple levels of the auditory pathway in reeler mice. These findings suggest that Reelin is essential for the proper structural development of auditory relay nuclei, and that its absence leads to widespread anatomical disorganization across both cortical and subcortical auditory regions. This structural disarray likely underlies the functional auditory deficits observed in reeler mice and underscores the critical role of Reelin in the formation of central auditory circuits.

Indexed as

Auditory pathwayCytoarchitectureMyeloarchitecturereeler

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What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.