Evidence map›Paper›PMID 42645761›Full record

ArticleForensic science, medicine, and pathology2026

Fatal diabetic ketoacidosis associated with excessive soft drink consumption: a case report.

Wei Zhang, Akiko Ishigami, Satoshi Hata, Miyu Osako, Philipp Nett, Yuko Ishida, Mizuho Nosaka, Hiroki Yamamoto, Yumi Kuninaka, Reiko Matsuki and 1 more

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Article in Forensic science, medicine, and pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Wei ZhangDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Akiko IshigamiDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan. a-ishi@wakayama-med.ac.jp.ORCID http://orcid.org/0000-0002-8393-5092
Satoshi HataDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Miyu OsakoDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Philipp NettInstitute of Forensic Medicine, Leipzig University, Johannisallee 28, 04103, Leipzig, Germany.
Yuko IshidaDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Mizuho NosakaDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Hiroki YamamotoDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Yumi KuninakaDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Reiko MatsukiDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Toshikazu KondoDepartment of Forensic Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of sudden and unexpected death due to diabetic ketoacidosis in a severely obese young woman (height, 146 cm; weight, 98 kg) with no prior diagnosis of diabetes mellitus but a history of prolonged excessive consumption of sugary beverages. Autopsy and histopathological findings revealed no fatal organic pathology except for severe fatty liver, and the toxicological examination was negative. Postmortem biochemical analysis showed markedly elevated serum glucose (1890 mg/dL), vitreous glucose (1900 mg/dL), glycated hemoglobin (13.7%), and acetone levels in the cardiac blood (65 µg/mL), peripheral blood (68 µg/mL), and urine (119 µg/mL). Tests for glutamic acid decarboxylase antibodies were negative. Based on these findings and the scene investigation, the cause of her death was determined to be diabetic ketoacidosis in the context of chronic excessive sugar intake, consistent with the phenomenon of "soft drink ketosis." This report highlights the essential role of postmortem biochemical analyses in elucidating the metabolic causes of sudden death.

Indexed as

AcetoneDiabetic ketoacidosis (DKA)GlucosePostmortem biochemistrySoft drink ketosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.