Evidence map›Paper›PMID 42645722›Full record

ArticleInflammopharmacology2026

Pharmacological evaluation of Schinus terebinthifolius leaf polysaccharides: from chemical profiling to anti-inflammatory and wound-healing applications.

Arij Bedoui, Ilhem Rjeibi, Walid Elfalleh, Anouar Feriani, Hamdi Bendif, Sulaiman A Alsalamah, Guillaume Pierre, Philippe Michaud, Fadwa Yahya, Zouhaier Abbes and 1 more

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Article in Inflammopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arij BedouiField Crop Laboratory, National Institute for Agricultural Research of Tunisia (INRAT), Carthage University, Tunis, Tunisia.
Ilhem RjeibiLaboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems, Faculty of Sciences of Gafsa, University of Gafsa, 2112, Gafsa, Tunisia.
Walid ElfallehDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), 11623, Riyadh, Saudi Arabia. wbelfallah@imamu.edu.sa.
Anouar FerianiLaboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems, Faculty of Sciences of Gafsa, University of Gafsa, 2112, Gafsa, Tunisia.
Hamdi BendifDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), 11623, Riyadh, Saudi Arabia.
Sulaiman A AlsalamahDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), 11623, Riyadh, Saudi Arabia.
Guillaume PierreUniversité Clermont Auvergne, Clermont Auvergne INP, CNRS, Institut Pascal, 63000, Clermont-Ferrand, France.
Philippe MichaudUniversité Clermont Auvergne, Clermont Auvergne INP, CNRS, Institut Pascal, 63000, Clermont-Ferrand, France.
Fadwa YahyaCollege of Computer Engineering and Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Zouhaier AbbesField Crop Laboratory, National Institute for Agricultural Research of Tunisia (INRAT), Carthage University, Tunis, Tunisia.
Nizar TliliResearch Laboratory for Sciences and Technologies of Environment, LR16ES09, High Institute of Sciences and Technologies of Environment Borj Cédria, Carthage University, Ben Arous, Tunisia. nizar.tlili@isste.ucar.tn.

Funding

Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University IMSIU-DDRSP-RP2601
6 · The paper itself

Abstract

This study aimed to characterize the physicochemical profile of polysaccharides from Schinus terebinthifolius leaf (PSTL) and evaluate their antioxidant, analgesic, anti-inflammatory, and wound-healing potential. Colorimetric analyses revealed a total carbohydrate content of 41% (w/w), a total protein content of 8.5% (w/w), and a total phenol content of 1.1% (w/w). Fourier-transformed infrared spectroscopy (FT-IR) identified characteristic functional groups, including O-H, C-H, and C=O. Ultraviolet-visible (UV-Vis) spectroscopy indicated low nucleic acid levels. X-ray diffraction (XRD) analysis demonstrated that these polysaccharides displayed a predominantly amorphous structure with partially ordered crystalline regions. Gas chromatography-mass spectrometry (GC-MS) analysis revealed the following molar ratios: glucose (4.19%), galacturonic acid (10.9%), galactose (9.01%), arabinose (9.2%), rhamnose (1.66%), and xylose (65.03%). These findings were consistent with the nuclear magnetic resonance (NMR) data. The functional tests showed that PSTL demonstrated strong emulsifying, foaming, and oil- and water-retention capacities. The biological evaluation revealed significant, concentration-dependent antioxidant activities (IC

Indexed as

Anti-Inflammatory AgentsPlant ExtractsPlant LeavesPolysaccharidesSchinusWound HealingAnimalsAntioxidantsEdemaGas Chromatography-Mass SpectrometryMaleMiceRatsSpectroscopy, Fourier Transform InfraredX-Ray DiffractionAnti-Inflammatory AgentsAntioxidantsPlant ExtractsPolysaccharidesBiological activitiesFunctional propertiesPolysaccharides

Identifiers

PMID42645722

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.