Evidence map›Paper›PMID 42645615›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Gastric emptying after athletic carbohydrate supplementation: implications for orthopaedic trauma patients.

Arissa M Torrie, Scott Tindal, Zachary Wilhelm, Karan Kommu, Anthony D Harris, Gerard P Slobogean, Robert V O'Toole, Nathan N O'Hara

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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Arissa M TorrieUniversity of Maryland School of Medicine, Baltimore, USA.
Scott TindalThrive AI Labs, Fuelin, San Francisco, USA.
Zachary WilhelmUniversity of Maryland School of Medicine, Baltimore, USA.
Karan KommuUniversity of Maryland School of Medicine, Baltimore, USA.
Anthony D HarrisUniversity of Maryland School of Medicine, Baltimore, USA.
Gerard P SlobogeanUniversity of California, Irvine, Irvine, USA.
Robert V O'TooleUniversity of Maryland School of Medicine, Baltimore, USA.
Nathan N O'HaraUniversity of California, Irvine, Irvine, USA. nnohara@hs.uci.edu.ORCID https://orcid.org/0000-0003-0537-3474

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No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePreoperative carbohydrate drinks are standard protocols for elective cases, but are often avoided before orthopaedic trauma surgery over concern for delayed gastric emptying and aspiration risk. Endurance-athlete carbohydrate formulations are engineered for rapid gastric emptying and may offer metabolic support without added aspiration risk. This study assessed gastric emptying in healthy volunteers to establish baseline profiles before trauma-patient testing.

methodsSixteen healthy adults received 1 or 2 products (Maurten or Precision Fuel & Hydration [PFH]). In carbohydrate gel supplementation phase, participants consumed a gel, fasted ≥ 8 h, then underwent baseline gastric ultrasound. In carbohydrate liquid supplementation phase, they consumed a 500 mL drink, with gastric ultrasounds every 15 min for up to 2 h. The primary endpoint was gastric volume < 1.5 mL/kg (low aspiration risk); the secondary endpoint additionally required clear or empty gastric content. Gastric volumes were compared with linear regression; time to threshold used restricted mean time estimation.

resultsIn phase 1, 15/16 (94%) had gastric volumes < 1.5 mL/kg after gel (median, 0.7 mL/kg; IQR, 0.5 to 1.1), with no significant difference between products (mean difference, 0.1 mL/kg; 95% CI - 0.2 to 0.4; p = 0.45). In phase 2, 14/16 (88%) reached the threshold within a restricted mean time of 68 min (95% CI 49 to 88). Maurten reached it 33 min faster than PFH (95% CI 0 to 66; p = 0.05).

conclusionsIn healthy volunteers, these gels and drinks reached low-aspiration-risk gastric volumes within clinically meaningful timelines, supporting evaluation for preoperative metabolic support in orthopaedic trauma patients.

Indexed as

Dietary CarbohydratesDietary SupplementsGastric EmptyingStomachAdultFemaleHealthy VolunteersHumansMaleOrthopedic ProceduresPreoperative CareRespiratory AspirationUltrasonographyYoung AdultDietary CarbohydratesAspirationCarbohydrate supplementationGastric emptyingGastric residual volumeOrthopaedic traumaPoint-of-care ultrasoundPreoperative fasting

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.