Evidence map›Paper›PMID 42645567›Full record

ArticleSurgery today2026

Impact of laparoscopic repeat hepatectomy on the outcomes of recurrent hepatocellular carcinoma.

Shoichi Inokuchi, Tetsuya Maeda, Satoshi Tsutsumi, Kenji Umeda, Takahiro Terashi, Toshio Bandoh, Masahiko Ikebe, Tohru Utsunomiya

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shoichi InokuchiDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan. Show.o.w1356@gmail.com.ORCID http://orcid.org/0000-0001-9522-7504
Tetsuya MaedaDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.
Satoshi TsutsumiDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.
Kenji UmedaDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.
Takahiro TerashiDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.
Toshio BandohDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.
Masahiko IkebeDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.
Tohru UtsunomiyaDepartment of Surgery, Oita Prefectural Hospital, 2-8-1 Bunyou, Oita, 870- 8511, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study compared the clinical background, surgical factors, and short- and long-term outcomes of patients who underwent laparoscopic versus open surgery for recurrent hepatocellular carcinoma (HCC). Furthermore, we investigated whether surgical factors were influenced by the use of the Pringle maneuver and adhesion prevention agents in previous laparoscopic surgeries.

methodsWe retrospectively analyzed the clinicopathological factors and outcomes of 106 consecutive patients who underwent repeat hepatectomy for recurrent hepatocellular carcinoma between January 2010 and December 2025.

resultsSixty-seven patients underwent laparoscopic hepatectomy (laparoscopic group), whereas 39 underwent open hepatectomy or conversion from laparoscopic to open surgery (open group). The open group had fewer women, more anatomical resections, a higher proportion of prior open liver resections, and a larger tumor size than the laparoscopic group. The open group had poorer recurrence-free and overall survival rates than the laparoscopic group. Surgery without the Pringle maneuver had a shorter surgical time, less blood loss, and fewer postoperative complications than surgery with the Pringle maneuver. The use of adhesion inhibitors before liver resection did not significantly affect operation time, blood loss, or postoperative complications.

conclusionsAttempting laparoscopic surgery for repeat hepatectomy is a reasonable option for patients with recurrent hepatocellular carcinoma.

Indexed as

Recurrent hepatocellular carcinomaRepeat hepatectomySurgical procedure

Identifiers

PMID42645567

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.