Evidence map›Paper›PMID 42645283›Full record

ArticleBiomimetics (Basel, Switzerland)2026

High-Performance Regenerated Silk Fibers as Building Blocks of Tissue Scaffolds: The European THOR Project.

José Pérez-Rigueiro, Atocha Guedán-Durán, Fivos Panetsos, Gianna Arencibia, Gustavo V Guinea, Luis Colchero, Miriam Quero, Jaime Espinosa, Alessandro Rizzi, Tando Maduna and 9 more

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

José Pérez-RigueiroBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Spain.ORCID 0000-0001-8298-8398
Atocha Guedán-DuránBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Spain.ORCID 0000-0002-0544-9574
Fivos PanetsosBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Spain.
Gianna ArencibiaBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Spain.
Gustavo V GuineaBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Spain.
Luis ColcheroBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Spain.ORCID 0000-0002-9673-0061
Miriam QueroCentro de Tecnología Biomédica (CTB), Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Spain.
Jaime EspinosaCentro de Tecnología Biomédica (CTB), Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Spain.
Alessandro RizziCentro de Tecnología Biomédica (CTB), Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Spain.
Tando MadunaDepartment of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0002-8758-1463
Anna PanchoDepartment of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Marsela HakaniDepartment of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Andreas VlachosDepartment of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0002-2646-3770
Julia Sepúlveda-DíazMicrofluidics Innovation Center S.A.S., 75011 Paris, France.ORCID 0000-0001-7977-476X
Alan MorinMicrofluidics Innovation Center S.A.S., 75011 Paris, France.
Michele PapaSYSBIO Centre of Systems Biology, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0002-6609-7453
Giovanni CirilloLaboratory of Neuronal Networks Morphology and Systems Biology, Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-3183-8773
Assunta VirtuosoLaboratory of Neuronal Networks Morphology and Systems Biology, Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-5304-247X
Ciro De LucaLaboratory of Neuronal Networks Morphology and Systems Biology, Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-8146-5736

Funding

Comunidad de Madrid MINA-CM P2022-BMD-7236Comunidad de Madrid TecNanoBio TEC-2024/TEC-158European Commission Grant Agreement number 101099719European Commission Grant Agreement number 101130454Ministerio de Ciencia, Innovación y Universidades grant PID2023-152058OB-I00
6 · The paper itself

Abstract

The European Pathfinder THOR project envisages the creation of a vascularized fragment of tissue that can be implanted in a patient using regenerated silk fibers as its building blocks. The selection of regenerated silk as the main building block of the scaffold relies heavily on its outstanding biocompatibility in comparison with either other artificial polymeric fibers or even natural silk fibers. Additionally, regenerated fibers produced through the Dynamic Dope Destabilization Spinning (D3S

Indexed as

endothelial cellorganotypic sliceregenerated silkspinningtissue engineering

Identifiers

PMID42645283
PMCPMC13509958

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.