Evidence map›Paper›PMID 42645280›Full record

ArticleBiomimetics (Basel, Switzerland)2026

Regenerative Performance and Structural Persistence of Silk Fibroin Matrices in Human Infected and Non-Infected Ex Vivo Wounds.

Sophie C Liegenfeld, Niklas P Straub, Nicolas Krueger, Mandy Dittmer, Arianna Delle Coste, Jan T Strenge, Markus Geissen, Sophie C Rhode, Wolfgang R Streit, Ralf Smeets and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sophie C LiegenfeldDepartment for Vascular Medicine, Translational Wound Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0009-0007-1139-3531
Niklas P StraubDepartment for Vascular Medicine, Translational Wound Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Nicolas KruegerDepartment for Vascular Medicine, Translational Wound Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Mandy DittmerDepartment for Vascular Medicine, Translational Wound Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Arianna Delle CosteDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Jan T StrengeDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Markus GeissenDepartment for Vascular Medicine, Translational Wound Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0009-0004-0393-8018
Sophie C RhodeDepartment of Plastic, Reconstructive and Aesthetic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Wolfgang R StreitDepartment of Microbiology and Biotechnology, University of Hamburg, 20148 Hamburg, Germany.
Ralf SmeetsDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-0207-5474
Ewa K StuermerDepartment for Vascular Medicine, Translational Wound Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-4193-4857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biodegradable biomaterials are promising candidates for regenerative wound care, yet their performance under infection-driven conditions remains poorly understood. This study evaluated the regenerative efficacy and structural persistence of a silk fibroin membrane and electrospun nonwoven matrix using a human ex vivo full-thickness skin wound model under non-infected and bacterially infected conditions. Complementary in vitro degradation assays assessed matrix durability following exposure to

Indexed as

biofilm infectionbiomaterial degradationex vivo skin modelsilk fibroinwound healing

Identifiers

PMID42645280
PMCPMC13510087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.