ArticleBiomimetics (Basel, Switzerland)2026
Effect of Bond Strength of Chitosan Containing Cavity Disinfectant on Deep or Superficial Dentin.
Article in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Chlorhexidine (CHX) has been widely reported as an inhibitor of matrix metalloproteinases (MMPs), contributing to the preservation of dentin bond integrity, while chitosan (CS) has been proposed as a natural biomodifier with potential collagen-stabilizing and cross-linking effects on the dentin matrix. These properties make both agents relevant candidates for improving the durability of adhesive interfaces. This in vitro study evaluated the effect of CS- and CHX-containing cavity disinfectants on the microtensile bond strength (µTBS) of a two-step self-etch adhesive applied to superficial and deep dentin. Forty-eight sound human molars were randomly assigned to superficial and deep dentin groups, which were further subdivided according to surface treatment: control (no treatment), 2% CHX, and 2.5% CS. A two-step self-etch adhesive system (Clearfil SE Bond) and resin composite were applied according to the manufacturers' instructions. After storage and thermocycling, beam-shaped specimens were prepared and subjected to µTBS testing. Data were analyzed using appropriate statistical methods, and significance was set at
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