ArticleCells2026
A Novel Chorioallantoic Membrane (CAM) Setup to Investigate Angiogenic Effects of Extracorporeal Shock Wave Therapy (ESWT).
Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Extracorporeal shock wave therapy (ESWT) is a well-known biophysical therapy that offers several beneficial effects, including a presumed increase in the growth of blood vessels. The chorioallantoic membrane (CAM) assay is a well-established in vivo model for studying angiogenesis. The aim of this study was to develop an experimental setup to apply ESWT to CAM in a three-step process and investigate the vascular response. First, we conducted virtual simulations of various shock-wave application setups to CAM and subsequently tested them in preliminary studies to evaluate their feasibility. In the final stage, we employed the most suitable protocol to investigate the angiogenic effects of shock wave therapy in practical applications. Our findings suggest that ESWT increases the number of vessels in CAM. In the final biological experiment (
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