Evidence map›Paper›PMID 42644930›Full record

ArticleGels (Basel, Switzerland)2026

Polyelectrolyte Microcapsules Enhance the Stability of β-Galactosidase Under Simulated Gastrointestinal Conditions.

Yuri S Chebykin, Aleksandr L Kim, Sergey A Tikhonenko

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuri S ChebykinInstitute of Theoretical and Experimental Biophysics Russian Academy of Science, Institutskaya St., 3, 142290 Puschino, Russia.
Aleksandr L KimMoscow Polytechnic University (Moscow Polytech), Bolshaya Semyonovskaya Str., 38, 107023 Moscow, Russia.ORCID 0000-0002-8129-9635
Sergey A TikhonenkoInstitute of Theoretical and Experimental Biophysics Russian Academy of Science, Institutskaya St., 3, 142290 Puschino, Russia.ORCID 0000-0002-0537-9537

Funding

The P.L. Kapitsa grant program third roundThe State Assignment of the Russian Federation 075-00224-26-02
6 · The paper itself

Abstract

Oral enzyme replacement therapy for lactase deficiency is limited by the rapid degradation of free β-galactosidase in the gastrointestinal tract. To overcome this, β-galactosidase was encapsulated into polyelectrolyte microcapsules (PMCs) via layer-by-layer assembly using MnCO

Indexed as

enzyme stabilitylactase deficiencymanganese carbonatepolyelectrolyte microcapsulesβ-galactosidase

Identifiers

PMID42644930
PMCPMC13512660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.