Evidence map›Paper›PMID 42644636›Full record

ReviewJournal of virology2026

NS-segment-based reporter influenza A viruses: engineering strategy, applications, and limitations.

Ramya S Barre, Himadri Nath, Aitor Nogales, Elsayed M Abdelwhab, Ahmed M Elsayed, Luis Martinez-Sobrido

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramya S BarreTexas Biomedical Research Institute, San Antonio, Texas, USA.
Himadri NathTexas Biomedical Research Institute, San Antonio, Texas, USA.
Aitor NogalesCenter for Animal Health Research, CISA-INIA-CSIC, Madrid, Spain.ORCID 0000-0002-2424-7900
Elsayed M AbdelwhabInstitute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Isle of Riems, Greifswald, Germany.
Ahmed M ElsayedTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0002-2878-5714
Luis Martinez-SobridoTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0001-7084-0804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reporter-expressing recombinant influenza A viruses (IAVs) have emerged as powerful tools for studying viral infection, host-pathogen interactions, and the identification and characterization of prophylactic and/or therapeutic countermeasures for the treatment of IAV infections. By incorporating a reporter gene, such as fluorescent, recombinase, or luciferase proteins, into the viral genome, these genetically engineered recombinant IAVs enable real-time visualization and quantification of infection

Indexed as

Genes, ReporterGenetic EngineeringInfluenza A virusViral Nonstructural ProteinsAnimalsHumansLuciferasesVirus ReplicationLuciferasesViral Nonstructural Proteinsantiviral bioassayIAVluciferasereporter geneVenusviral infection

Identifiers

PMID42644636
PMCPMC13595980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.