Evidence map›Paper›PMID 42644346›Full record

ArticleAnnals of medicine2026

Epidemiology and outcomes of invasive fungal infections in patients with mature T-cell and NK-cell lymphomas.

Ming-Tao Tsai, Pao-Yu Chen, Tai-Chung Huang, Jann-Tay Wang, Wen-Chien Chou, Yee-Chun Chen

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Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ming-Tao TsaiDepartment of Medicine, National Taiwan University Cancer Center, Taipei, Taiwan.ORCID 0009-0006-0139-8067
Pao-Yu ChenDivision of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0001-9499-1842
Tai-Chung HuangDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Jann-Tay WangDivision of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Wen-Chien ChouDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0003-2967-698X
Yee-Chun ChenDivision of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInvasive fungal infection (IFI) causes poor outcomes in haematological malignancies, but data in mature T-cell and NK-cell lymphomas (T/NKCL) are scarce. We aimed to define epidemiology and outcomes of IFI in this population. MATERIALS AND

methodsThis retrospective study enrolled adult patients with T/NKCL between 2019 and 2024. Proven and probable IFI were defined according to the 2020 EORTC/MSGERC criteria. Multivariable logistic regression was used to identify factors associated with IFI and death.

resultsAmong 203 patients, 43 (21%) developed 52 IFI episodes, including invasive yeast infections (IYI,

conclusionsIFI is common and confers substantial mortality in patients with T/NKCL, with distinct pathogen-specific timing. These findings support early risk stratification and targeted preventive strategies in this high-risk population.

Indexed as

Invasive Fungal InfectionsLymphoma, Extranodal NK-T-CellLymphoma, T-CellAdultAgedFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedPneumonia, PneumocystisRetrospective StudiesRisk FactorsImmunocompromised hostsinvasive mould infectioninvasive yeast infectionmortalityPneumocystis jirovecii pneumonia

Identifiers

PMID42644346
PMCPMC13520847

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