ArticleAnnals of medicine2026
Shrunken pore syndrome increased the risk of acute kidney injury after cardiac surgery: a cohort study.
Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundShrunken pore syndrome (SPS), as a selective glomerular hypofiltration syndrome, has received increasing attention. Therefore, we hypothesised that patients with SPS have a high risk of postoperative acute kidney injury (AKI).
methodsThis trial was a retrospective cohort study. Patients who received isolated coronary artery bypass grafting (CABG) in the Affiliated Hospital of Qingdao University were continuously reviewed. Estimated glomerular filtration rates (eGFRs) were calculated by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. The SPS was defined as an eGFR based on cystatin C < 70% of the eGFR based on creatinine. Postoperative AKI was diagnosed according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria, and the occurrence of AKI within seven days after surgery was followed up.
resultsA total of 1277 patients were included, and the incidence of postoperative AKI was 23.2% (296/1277), and 12.8% (164/1277) patients were diagnosed with SPS before surgery. The incidence of AKI in the SPS group was significantly higher than that in the non-SPS group (33.5% vs. 21.7%, adjOR = 1.613, 95%CI 1.121-2.322,
conclusionsSPS is an independent risk factor for AKI after CABG. It will bring a new insight for an accurate clinical assessment of the risk of postoperative AKI.
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