Evidence map›Paper›PMID 42644197›Full record

ArticleJournal of craniovertebral junction & spine

Posterior C1-C2 screw-rod salvage for Chiari I malformation with atlantoaxial instability after failed foramen magnum decompression.

Shengli Guo, Luokai Huangfu, Guangyu Qiao

Abstract read
In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Shengli Guo *Department of Neurosurgery, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Luokai Huangfu *Department of Neurosurgery, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Guangyu QiaoDepartment of Neurosurgery, The First Medical Center, Chinese PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chiari I malformation secondary to atlantoaxial instability requires reduction and stabilization. When initial foramen magnum decompression (FMD) is performed without recognition of this instability, subsequent salvage surgery is technically demanding and carries substantial risk. Objective: The objective of this study was to evaluate the clinical and radiological outcomes of posterior C1-C2 screw-rod salvage surgery in patients with Chiari I malformation and atlantoaxial instability following failed FMD. Materials and Methods: We retrospectively analyzed 21 consecutive patients with Chiari I malformation and atlantoaxial instability who underwent posterior C1-C2 screw-rod salvage surgery after failed FMD. Atlantoaxial instability was defined by dynamic imaging showing an atlantodental interval (ADI) >3 mm on flexion or vertical odontoid protrusion above Wackenheim's line (WL). Clinical status was assessed with the Japanese Orthopedic Association (JOA) score. Radiological outcomes were evaluated by ADI, odontoid tip-WL distance, and cervicomedullary angle (CMA) on computed tomography (CT) and magnetic resonance imaging. Results: The cohort comprised 14 males and 7 females (mean age: 39.33 ± 8.2 years). Screws were successfully placed in all C1 lateral masses and in 40 of 42 C2 pedicles; in the remaining two cases, C2 inferior articular facet screws were used. Postoperative CT showed complete horizontal reduction (ADI <3 mm) in 90.5% and satisfactory vertical reduction in 85.7%. The mean JOA score improved from 9.8 preoperatively to 14.1 at 6-month follow-up ( Conclusion: Posterior C1-C2 screw-rod salvage surgery is a safe and effective strategy for Chiari I malformation with atlantoaxial instability after failed FMD. This posterior-only technique provides simultaneous reduction, decompression, and stabilization, yielding significant clinical improvement and reliable fusion even in the previously operated, scarred craniocervical field.

Indexed as

Atlantoaxial instabilityChiari I malformationposterior C1–C2 fixationrevision surgerysalvage procedure

Identifiers

PMID42644197
PMCPMC13506107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.