Evidence map›Paper›PMID 42644115›Full record

ArticleInternational journal of women's health2026

Epidemiological Transition in Health Risks and Disease Burden Among Women of Childbearing Age in East Asia and the Pacific, 1990-2023.

Huayu Huang, Ziyuan Xu, Yong Zhang, Jianbo Wei

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Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Huayu HuangDepartment of Dermatology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.ORCID 0009-0005-1280-3278
Ziyuan XuKey Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Yong ZhangDepartment of Dermatology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Jianbo WeiDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.ORCID 0000-0003-0463-9939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Women of childbearing age (WCBA) in East Asia and Pacific (EAP) have experienced rapid epidemiological change, yet research focus and policy priorities often remain concentrated on maternal survival. We aimed to characterize three-decade comprehensive transitions in causes and risk factors, and quantify cross-country gaps. Methods: We analyzed modelled GBD 2023 estimates for women aged 15-49 in the EAP region from 1990 to 2023, quantifying the disease burden by disability-adjusted life years (DALYs). Long-term trends were summarized using estimated annual percentage changes (EAPC), and investigated changes before and after the COVID-19 pandemic. Frontier analysis quantifies the disparities in preventable disease burden across countries. Results: From 1990 to 2023, the age-standardized DALY rate among WCBA in EAP declined from 35,218 to 27,534 per 100,000, yet non-communicable diseases expanded their share from 62.3% to 75.7%. By 2023, gynecological disorders, depression, and headache disorders constituted the leading causes of burden. Among risk factors, high body-mass index risk increased significantly since 1990, and became the top risk factor (ASDR = 583.5 per 100,000) in 2023. During the acute pandemic phase, DALYs rose in 33 of 35 EAP regions. Frontier analysis revealed a 2.8-fold disparity in avoidable burden across countries at comparable development levels, with distance-to-frontier in ASDR ranging from 0.35 (Nauru) to 0.98 (China) in 2023. Conclusion: The WCBA disease burden in EAP has transitioned from maternal and infectious conditions toward chronic, metabolic, and disability-related disorders, with significant persistent intra-regional disparities. Health systems should pivot from isolated reproductive care toward integrated life-course surveillance, embedding NCD and mental health services within routine women's health platforms to address this evolving burden.

Indexed as

disability-adjusted life yearsEast Asia and Pacificepidemiological transitionglobal burden of diseasesocio-demographic indexwomen of childbearing age

Identifiers

PMID42644115
PMCPMC13505553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.