Evidence map›Paper›PMID 42644113›Full record

ArticleJournal of human immunity2026

Kavitha Thiagarajan, Huan Vinh Dong, Caroline Y Kuo, Timothy J Thauland, Sheeja Pullarkat, Manish J Butte, Maria I Garcia-Lloret, Karin Nielsen-Saines

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of human immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kavitha Thiagarajan *Division of Allergy, Immunology & Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0009-0008-2595-3461
Huan Vinh Dong *Pediatric Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-6370-1811
Caroline Y KuoDivision of Allergy, Immunology & Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-9302-0187
Timothy J ThaulandDivision of Allergy, Immunology & Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-4121-0453
Sheeja PullarkatDepartment of Pathology, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-1490-2374
Manish J ButteDivision of Allergy, Immunology & Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-4490-5595
Maria I Garcia-LloretDivision of Allergy, Immunology & Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-3763-7702
Karin Nielsen-SainesPediatric Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-1742-5211

Funding

Collaborative multi-site project to speed the identification and management of rare genetic immune diseasesR01AI153827 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BUTTE, MANISH J, PASANIUC, BOGDAN · 2021 to 2025
$3.9M
Addressing Evolving Infectious ThreatsT32AI177290 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Risa M. Hoffman, Karin Nielsen · 2023 to 2026
$1.3M
NIAID NIH HHS R01 AI153827NIAID NIH HHS T32 AI177290
6 · The paper itself

Abstract

Signal transducer and activator of transcription 1 (STAT1) defects present with diverse clinical phenotypes. We describe an unusual genotype/phenotype: disseminated mycobacterial infection without chronic mucocutaneous candidiasis in the context of a pathogenic STAT1 gain-of-function variant (p.Lys388Glu). To our knowledge, this is the first report of such a case.

Identifiers

PMID42644113
PMCPMC13505569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.