Evidence map›Paper›PMID 42644088›Full record

ArticleARYA atherosclerosis2026

Incidence and risk factors for cardiovascular mortality in Iranian adults: Findings from a 10year Yazd Healthy Heart Project Study.

Mohammadtaghi Sarebanhassanabadi, Samira Qaderi, Mahdi Karimi, Lida Hosseini, Pedro Marques-Vidal, Ahmad Shajari, Hamideh Mihanpour, Sima Mozafari

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Article in ARYA atherosclerosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mohammadtaghi SarebanhassanabadiYazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Samira QaderiIslamic Azad University, Tehran Medical Branch, Tehran, Iran.
Mahdi KarimiIslamic Azad University, Tehran Medical Branch, Tehran, Iran.
Lida HosseiniYazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Pedro Marques-VidalDepartment of Internal Medicine, BH10-642, Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.
Ahmad ShajariDepartment of Medicine, YMS. C., Islamic Azad University, Yazd, Iran.
Hamideh MihanpourDepartment of Occupational Health Engineering, Genetic and Environmental Adventures Research Center, School of Abarkouh Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Sima MozafariYazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is the leading cause of death worldwide, with a growing burden in low- and middle-income countries. Given the increasing CVD mortality in Iran and the limited evidence on long-term lifestyle determinants, a cohort study is needed to examine the effects of related factors.

methodsA total of 2,000 adults, including 1,000 men and women aged 20 to 74 years, were enrolled in a population-based cohort study in Yazd, Iran, from 2005 to 2006, with a mean follow-up of 10 years. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for CVD mortality in relation to demographic, economic status, educational, and lifestyle factors.

resultsDuring follow-up, 83 CVD deaths occurred (5.4%). The mortality rate was 6.8% in men and 3.8% in women. After adjustment for hypertension, diabetes, and hypercholesterolemia, significant predictors of CVD mortality included age ≥65 years (HR = 3.63, 95% CI: 2.28-5.77), male sex (HR = 2.29, 95% CI: 1.31-3.34), and smoking (HR = 1.95, 95% CI: 1.21-3.13). In contrast, moderate physical activity was associated with a lower risk of mortality (HR = 0.38, 95% CI: 0.17-0.84), and high school education was also protective (HR = 0.49, 95% CI: 0.25-0.98). In subgroup analyses among men, age ≥65 years, moderate physical activity, and high school education remained significant predictors of CVD mortality (P < 0.05).

conclusionAge 65 years or older, smoking, and male sex increased the risk of CVD mortality in this Iranian cohort. Physical activity and higher educational attainment were associated with a reduced risk of CVD mortality.

Indexed as

Cardiovascular DiseaseCohort StudiesIncidenceMortality; Risk Factors

Identifiers

PMID42644088
PMCPMC13505311

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