Evidence map›Paper›PMID 42644045›Full record

ArticleARYA atherosclerosis2026

Association of SYNTAX score, ankle-brachial index, and toe-brachial index with peripheral arterial disease following CABG.

Jamal Moosavi, Ali Mohamad Nasirian, Amir Ghaffari Jolfayi, Parham Sadeghipour, Bahram Mohebi, Seyed Mohammadjavad Hosseini, Ermia Tabandeh, Roya Hamrahi, Amin Elahifar, Vida Hamrahi and 3 more

Abstract read
In one paragraph

Article in ARYA atherosclerosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Jamal MoosaviVascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Ali Mohamad NasirianVascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Amir Ghaffari JolfayiVascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Parham SadeghipourVascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Bahram MohebiVascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Seyed Mohammadjavad HosseiniVascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Ermia TabandehRajaie Cardiovascular Medical and Research Center, Rajaie School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Roya HamrahiRajaie Cardiovascular Medical and Research Center, Rajaie School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Amin ElahifarRajaie Cardiovascular Medical and Research Center, Rajaie School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Vida HamrahiRajaie Cardiovascular Medical and Research Center, Rajaie School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mansoor NamaziRajaie Cardiovascular Medical and Research Center, Rajaie School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Enayatollah NooriGeneral Physician, Qom University of Medical Sciences, Qom, Iran.
Abdolreza DayaniRajaie Cardiovascular Medical and Research Center, Rajaie School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeripheral arterial disease (PAD) is a common comorbidity in patients undergoing coronary artery bypass grafting (CABG) and is associated with increased morbidity. Early identification of PAD in this population is clinically important; however, the relationship between coronary disease complexity and peripheral arterial involvement remains unclear.This study aimed to evaluate the association of the SYNTAX score, ankle-brachial index (ABI), and toe-brachial index (TBI) with the development of peripheral arterial disease following CABG.

methodsIn this retrospective study, 87 patients who underwent CABG were evaluated four years after surgery for the presence of PAD. Baseline SYNTAX score, ABI, and TBI were measured prior to CABG. PAD was diagnosed based on clinical symptoms in combination with abnormal ABI and/or TBI findings and was confirmed by Doppler ultrasonography when indicated. Associations between SYNTAX score, ABI, TBI, and PAD were analyzed using appropriate statistical tests.

resultsDuring the follow-up period, 7 patients (8.0%) developed PAD. Diabetes mellitus was significantly more prevalent among patients with PAD compared to those without PAD (85.7% vs. 45.0%, P = 0.039). Right ABI (P = 0.005), left TBI (P = 0.008), and right TBI (P = 0.010) were significantly associated with PAD, whereas left ABI was not. Although the SYNTAX score was not directly associated with PAD incidence, higher SYNTAX scores were significantly correlated with greater reductions in both left ABI (r = -0.296, P = 0.005) and right ABI (r = -0.220, P = 0.040) 4 years after CABG.

conclusionPeripheral arterial disease following CABG was significantly associated with diabetes mellitus and with lower ABI and TBI values, particularly in the right lower extremity. While the SYNTAX score was not directly associated with PAD occurrence, it was correlated with longitudinal declines in ABI, suggesting an association between coronary disease complexity and systemic vascular dysfunction.

Indexed as

Ankle Brachial IndexCoronary Artery Bypass SurgeryCoronary SYNTAX ScorePeripheral Artery DiseaseToe Brachial Index

Identifiers

PMID42644045
PMCPMC13505305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.