ArticleClinical, cosmetic and investigational dermatology2026
Effects of Moist Wound Healing Strategy on Healing Time of Burn Wound Donor Sites and Patients' Depression/Anxiety Symptoms.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to compare the effects of a Moist Wound Healing (MWH) strategy using Sanyrene liquid dressing versus Traditional Dry Care (TDC) with infrared lamp irradiation on donor site healing time and psychological symptoms in burn patients. Methods: A retrospective cohort of 173 patients undergoing split-thickness skin graft surgery was divided into TDC (n=92) and MWH (n=81) groups based on documented postoperative care. Healing time was assessed from postoperative day 7 until complete re-epithelialization. Pain was evaluated twice daily using the Numeric Rating Scale (NRS) during the 7-day intervention. Skin condition and scar quality were assessed via the Overall Dry Skin (ODS) score and Vancouver Scar Scale (VSS) at 1 and 3 months. Psychological symptoms were measured at 3 months using the Hospital Anxiety and Depression Scale (HADS). Results: The MWH group exhibited a significantly shorter mean healing time (13.23 days vs 16.85 days, P<0.001) and a higher proportion of wounds healed within 7 days (35.8% vs 17.39%, P=0.006). From day 4 onward, MWH patients reported lower NRS pain scores (eg, 2.51 vs 2.98 on day 7, P<0.001). At follow-up, the MWH group had better ODS and VSS scores (all P<0.05) and lower HADS-Anxiety (P=0.005) and HADS-Depression scores (P=0.002). Multivariate analysis confirmed MWH as an independent protective factor against non-healing within 7 days (OR=0.624, P=0.002). Conclusion: MWH with Sanyrene dressing is associated with faster donor site healing, reduced pain, improved skin and scar outcomes, and better psychological well-being compared to TDC in burn patients.
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