Evidence map›Paper›PMID 42643955›Full record

ArticleJournal of craniovertebral junction & spine

Partial C2 corpectomy with iliac/fibula bone graft and posterior instrumented fusion for C2 vertebral body lesions: An innovative approach.

Charan Makkina, Tony Varghese Panicker, Baylis Vivek Joseph

Abstract read
In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Charan MakkinaDepartment of Neurological Sciences, Christian Medical College and Hospital, Vellore - Ranipet Campus, Tamil Nadu, India.
Tony Varghese PanickerDepartment of Neurological Sciences, Christian Medical College and Hospital, Vellore - Ranipet Campus, Tamil Nadu, India.
Baylis Vivek JosephDepartment of Neurosurgery, Jerudong Park Medical Centre, BG3122, Brunei Darussalam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lesions of the C2 vertebral body represent a distinct and demanding subset of spinal pathology. The intricate anatomy of the upper cervical spine, characterized by its proximity to critical neurovascular structures, limited surgical corridors, and complex biomechanical demands, renders surgical intervention at this level particularly challenging. Anatomical Consideration and Surgical Rationale: The odontoid process (dens) of C2 plays a pivotal role in the stability of the craniovertebral junction. When the tip of the odontoid is preserved despite partial vertebral body destruction, it remains a reliable anchor point for spinal fusion. Exploiting this anatomical advantage allows for anterior uninstrumented bone graft placement, thereby minimizing surgical morbidity. Study Objective and Surgical Technique: This article presents a retrospective review of six patients who presented with partial destruction of the C2 vertebral body and were managed surgically. The operative strategy employed consisted of three key components: Anterior median C2 corpectomy-targeted resection of the diseased vertebral body while preserving viable bony structuresReconstruction with autologous bone graft-restoration of anterior column integrity using iliac crest or fibular graft, using the osteogenic and biomechanical properties of autologous materialPosterior stabilization - supplementary fixation to ensure construct stability. Significance and Conclusion: The findings of this review underscore the viability, safety, and clinical effectiveness of this surgical strategy (anterior corpectomy with uninstrumented fusion and posterior supplementary instrumented fusion) across a spectrum of pathological conditions affecting the C2 vertebra. By demonstrating its applicability in varied clinical scenarios, this technique offers a reproducible and practical framework for surgeons managing this challenging anatomical region.

Indexed as

Anterior column reconstructionbony tumorsC2 vertebraestructural autograftuninstrumented fusion

Identifiers

PMID42643955
PMCPMC13506115

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.