Evidence map›Paper›PMID 42643890›Full record

ReviewFrontiers in cell and developmental biology2026

Non-transport functions of motor proteins in corticogenesis.

Natalia Mitina, Alexandra Medyanik, Victor Tarabykin, Elena Kondakova

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natalia MitinaLaboratory of Genetics of Brain Development, Institute of Neurosciences, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia.
Alexandra MedyanikLaboratory of Genetics of Brain Development, Institute of Neurosciences, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia.
Victor TarabykinLaboratory of Genetics of Brain Development, Institute of Neurosciences, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia.
Elena KondakovaLaboratory of Genetics of Brain Development, Institute of Neurosciences, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral cortex development is a tightly coordinated sequence of interconnected processes: proliferation of neural progenitors, neuronal migration, neurite differentiation, axonal pathfinding, and synaptogenesis. Traditionally, motor proteins-dyneins, kinesins, and myosins-have been viewed as molecules mediating intracellular transport along the cytoskeleton. Nevertheless, data accumulated over the past decade provide compelling evidence for a fundamentally different, non-transport role of these proteins in nervous system development. This review systematizes current understanding of the non-transport functions of motor proteins at key stages of corticogenesis. We review the molecular mechanisms that enable dyneins, kinesins, and myosins to function as regulators of cortical development. We focus specifically on the causal relationship between disruptions to the non-transport functions of motor proteins and cortical developmental disorders, including microcephaly, lissencephaly, and agenesis of the corpus callosum.

Indexed as

cortical developmentdyneinkinesinmultipolar-to-bipolar transitionmyosinneural progenitor proliferationneurite outgrowthneuronal migration

Identifiers

PMID42643890
PMCPMC13504318

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.