Evidence map›Paper›PMID 42643833›Full record

ArticleAutism in adulthood2026

Understanding the Impact of Living Situation and Social Satisfaction on Depression and Substance Use in Autistic Young Adults Without Intellectual Disability.

María E Contreras-Pérez, Xiangyu Tao, Olivia Vezina, Anthony Spirito, Stephen J Sheinkopf, Casey A Cragin, Kristina M Jackson

Abstract read
In one paragraph

Article in Autism in adulthood, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María E Contreras-PérezRutgers Alcohol Research Center, Rutgers University, 57 US Highway 1 New Brunswick, NJ 08901 USA.
Xiangyu TaoRutgers Alcohol Research Center, Rutgers University, 57 US Highway 1 New Brunswick, NJ 08901 USA.
Olivia VezinaDepartment of Psychiatry and Human Behavior, Box G-BH, Providence, RI 02912, USA.
Anthony SpiritoDepartment of Psychiatry and Human Behavior, Box G-BH, Providence, RI 02912, USA.
Stephen J SheinkopfThompson Center for Autism & Neurodevelopment, University of Missouri, 205 Portland St, Columbia, MO 65201 USA.
Casey A CraginBoston Children's Hospital, Department of Psychiatry and Behavioral Sciences, 300 Longwood Ave, Boston, MA 02115.
Kristina M JacksonRutgers Alcohol Research Center, Rutgers University, 57 US Highway 1 New Brunswick, NJ 08901 USA.

Funding

Prevalence, Onset and Progression of Substance Use in Adolescents and Young Adults with Autism Spectrum DisordersR01AA029008 · NIAAA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Kristina Melia Jackson, STEPHEN J SHEINKOPF · 2021 to 2026
$4.1M
Integrating AI and Co-production to Analyze Communications in Social Media Substance Use Recovery GroupsK99DA064782 · NIDA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Xiangyu Tao · 2026 to 2026
$140k
NIAAA NIH HHS R01 AA029008NIDA NIH HHS K99 DA064782
6 · The paper itself

Abstract

Background: Autistic young adults face elevated risks for depression, and emerging evidence indicates that some engage in substance use. Residential status and social satisfaction may be related to these outcomes, yet little research has examined their interplay in autistic populations. Methods: Baseline data were drawn from 267 autistic young adults ages 18-24 (M=21.56; SD=1.76). Participants were predominantly female (65.63%), non-Hispanic White (75%), and enrolled in school (68.76%). Participants reported their current residential status, mental health, and substance use, and completed measures of social and role functioning, social satisfaction, and demographic characteristics. A unified mediation model tested whether social satisfaction mediated associations between residential status and (1) depression, (2) alcohol use, and (3) cannabis use, adjusting for relevant covariates. Results: Living alone, compared to living with a parental figure, was associated with greater social satisfaction, which in turn predicted fewer depression symptoms. In contrast, living alone or with friends or roommates was directly associated with elevated alcohol and cannabis use but showed no indirect effects through social satisfaction. Social satisfaction predicted lower depression but was not significantly related to alcohol or cannabis use. Conclusion: Residential status and social satisfaction jointly shape emotional and behavioral outcomes among autistic young adults. Independent living may enhance well-being when accompanied by fulfilling social connections, whereas peer cohabitation may increase exposure to substance use. Interventions that support autonomy, foster social engagement, and incorporate harm reduction strategies may be particularly valuable in promoting healthy transitions to adulthood for autistic individuals.

Indexed as

alcohol useanxietyAutism spectrum disorderCannabis usedepressionresidential statussocial satisfactionyoung adults

Identifiers

PMID42643833
PMCPMC13505494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.