ArticleJournal of pesticide science2026
Insecticidal effects of oxazosulfyl result from synaptic inhibition by targeting the vesicular acetylcholine transporter.
Article in Journal of pesticide science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Oxazosulfyl is the first insecticide in the sulfyl (alkylsulfone) class developed for rice protection. While the vesicular acetylcholine transporter (VAChT) has been proposed as its primary molecular target, its mode of action has not yet been extensively examined in major agricultural pests. In this study, we investigated the binding affinity of oxazosulfyl to VAChT derived from the brown planthopper (BPH), a significant rice pest, and evaluated the relationship between its insecticidal activity and binding affinity. Oxazosulfyl bound to VAChT, heterologously expressed in cultured cells, with a
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