ArticleDEN open2027
Clinical Outcomes of Multi-Hole Covered Self-Expandable Metal Stents for Malignant Distal Biliary Obstruction: A Retrospective Comparative Study With an Exploratory Evaluation of 6-mm Devices.
Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Covered self-expandable metal stents (CSEMS) are widely used for malignant distal biliary obstruction (MDBO), but cholecystitis, post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP), stent migration, and recurrent biliary obstruction (RBO) remain clinically important limitations. Multi-hole SEMS (MHSEMS) is a novel CSEMS designed to preserve side-branch drainage and reduce migration. We evaluated MHSEMS compared with conventional CSEMS and explored the potential impact of a newly available 6-mm MHSEMS. Methods: This retrospective single-center study included consecutive patients who underwent initial transpapillary SEMS placement for MDBO between September 2015 and December 2025. Study-I compared MHSEMS versus conventional CSEMS limited to 8-10 mm diameter stents. Study-II included MHSEMS cases only and compared 6-mm versus 8-10 mm MHSEMS. Outcomes included cholecystitis, PEP, RBO, time to RBO (TRBO), and RBO causes. Results: Study-I included 148 patients; median follow-up was 80.5 versus 81.5 days ( Conclusions: MHSEMS was associated with fewer cholecystitis events and migration and longer TRBO versus conventional CSEMS. The potential benefit of 6-mm MHSEMS for reducing PEP remains exploratory and requires confirmation in longer prospective studies.
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