Evidence map›Paper›PMID 42643511›Full record

ArticleCureus2026

Changes in Corneal Biomechanics and Wavefront Following Eyelid Surgery.

Khushdeep Abhaypal, Parul Chawla Gupta, Manpreet Singh, Manu Saini, Padma Thinlass, Pankaj Gupta

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khushdeep AbhaypalOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, IND.
Parul Chawla GuptaOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, IND.
Manpreet SinghOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, IND.
Manu SainiOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, IND.
Padma ThinlassOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, IND.
Pankaj GuptaOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study evaluated corneal biomechanics and wavefront aberrations in patients with eyelid masses and documented changes in these parameters following surgical excision in a Northwest Indian population through a prospective interventional study.

methodsTwenty eyes of 20 patients requiring surgical excision of eyelid masses were enrolled. Preoperative and postoperative assessments included a comprehensive ocular examination, corneal biomechanics evaluation using an ocular response analyzer, and wavefront aberrometry with the I-Trace system.

resultsCorneal biomechanics were assessed preoperatively and postoperatively in all patients. No statistically significant changes were observed in corneal hysteresis or corneal resistance factor following surgery, regardless of lesion location in the upper (P=0.458) or lower eyelids (P=0.154). Similarly, wavefront aberrations, including lower-order aberrations (LOAs), higher-order aberrations, spherical aberrations (SAs), coma, and trefoil, showed no significant postoperative differences overall. However, patients with lesions ≥5 mm in size exhibited significant changes in astigmatism, SAs (P=0.008), coma (P=0.050), and total LOAs (P=0.049) postoperatively. Patients with lesions ≥5 mm demonstrated significant postoperative changes in selected corneal wavefront parameters, whereas no significant changes were observed in corneal biomechanical parameters.

conclusionSurgical excision of larger eyelid masses (≥5 mm) is associated with significant postoperative changes in corneal wavefront parameters, particularly in astigmatism, SAs, coma, and LOAs, while corneal biomechanics remain stable. This highlights the role of lesion size in influencing corneal wavefront changes, warranting further investigation in larger cohorts.

Indexed as

corneal biomechanicseyelid mass‎eyelid surgeryocular response analyserwavefront aberrations

Identifiers

PMID42643511
PMCPMC13504124

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.