ArticleFrontiers in medicine2026
Biometric and ICL-related risk factors associated with suboptimal vault with implantable collamer lenses.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To comprehensively explore the biometry related to suboptimal vault (including low and high vault) after implantable collamer lens (ICL) implantation and the risk factors associated with ICL. Methods: This retrospective case-control study enrolled 180 patients with myopia and astigmatism who underwent EVO-V4c ICL implantation at Peking Union Medical College Hospital between January 2023 and December 2024. The normal vault group (NVG) was randomly selected from eligible patients during the same period to ensure balanced group sizes and reduce selection bias. Patients were divided into three groups based on the postoperative vault: low vault group (LVG, <250 μm, Results: The results indicated significant differences in age, ACD, WTW, ATA, AL, and CLR among the three groups of patients ( Conclusions: Low vault is independently associated with greater CLR, whereas high vault is independently linked to deeper ACD and higher SE. Age, WTW, ATA, and AL also demonstrate significant but varying associations with vault type. These findings underscore the importance of integrating CLR and ATA measurements into routine preoperative assessment. Employing a more individualized sizing strategy-particularly in patients with deeper ACD or pronounced CLR-could enhance vault predictability and improve postoperative safety.
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