Evidence map›Paper›PMID 42643408›Full record

ArticleFrontiers in veterinary science2026

Preliminary study on the effects of different dietary spermine levels on intestinal function, microflora, and metabolism in weaned Wuzhishan piglets.

Xinyu Xue, Tao Tang, Haojie Zhang, Limin Wei, Feng Wang, Zhe Chao, Hailong Liu, Yuwei Ren, Chengjun Hu, Ruiping Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyu Xue *Key Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.
Tao Tang *Tropical Crop Genetic Resource Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, China.
Haojie ZhangCollege of Animal Science and Technology, Guangxi University, Nanning, China.
Limin WeiKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.
Feng WangKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.
Zhe ChaoKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.
Hailong LiuKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.
Yuwei RenKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.
Chengjun HuTropical Crop Genetic Resource Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, China.
Ruiping SunKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, Hainan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Spermine has been shown to promote intestinal maturation and protect intestinal health. However, its potential as a dietary feed additive for improving intestinal health in Wuzhishan piglets remains unclear. In this study, eighteen weaned Wuzhishan piglets were randomly assigned to three groups ( Results: Dietary supplementation with 0.01% spermine significantly improved growth performance ( Conclusion: These findings suggest that dietary supplementation with 0.01% spermine can effectively alleviate weaning-induced intestinal dysfunction in Wuzhishan piglets by improving intestinal morphology, digestive enzyme activity, and immune responses, modulating the relative abundance of specific gut bacteria, and enhancing metabolic capacity.

Indexed as

growthintestinal florametabolismspermineWuzhishan pig

Identifiers

PMID42643408
PMCPMC13503206

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.