ArticleFrontiers in neurology2026
Eye movement characteristics and their correlation with cognitive function in cerebral small vessel disease.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to investigate the characteristics of eye movements and their correlation with cognition in patients with cerebral small vessel disease (CSVD). Methods: This was a cross-sectional study enrolling a total of 120 patients with CSVD admitted to Hebei General Hospital from January 2022 to October 2023. The videonystagmography (VNG) was completed, and the Montreal Cognitive Assessment (MoCA) was used to evaluate the patients' cognitive function. Patients were stratified into mild (0), moderate (1-2), and severe (3-4) groups based on a 4-point MRI score integrating white matter hyperintensities, lacunar infarcts, enlarged perivascular spaces, and cerebral microbleeds. Results: Decreased right saccade accuracy (OR = 0.923, 95% CI: 0.890 ~ 0.959, Conclusion: Eye movement characteristics in CSVD patients were significantly correlated with the total MRI load and cognitive function. This provides an important reference value for the early identification and assessment of CSVD severity.
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