Evidence map›Paper›PMID 42643383›Full record

ArticleFrontiers in oncology2026

Rapid commissioning of Brainlab Elements for SRS: end-to-end evaluation of Monte Carlo and pencil beam algorithm across homogeneous and heterogeneous phantom environments.

Bhuvaneswari Narayanan, Daniel Saenz, Nikos Papanikolaou, Neil Kirby, Doug Soltesz, Eva Galvan, Richard Tuli, Karl Rasmussen, Holly Paschal, Nema Bassiri-Gharb

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bhuvaneswari NarayananDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Daniel SaenzDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Nikos PapanikolaouDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Neil KirbyDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Doug SolteszDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Eva GalvanDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Richard TuliDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Karl RasmussenDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Holly PaschalDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.
Nema Bassiri-GharbDepartment of Radiation Oncology, University of Texas at San Antonio, San Antonio, TX, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Brainlab released a reference beam model that accelerates Brainlab Elements treatment planning system (TPS) commissioning process for stereotactic radiosurgery (SRS) using an Elekta Versa HD linear accelerator. A series of end-to-end (E2E) phantom studies were performed to evaluate the Monte Carlo (MC) and pencil beam (PB) dose calculation algorithms using the reference beam model released by Brainlab with Elements v4.0 and v4.5. Methods: A reduced set of water tank measurements of percent depth dose (PDD), beam profiles, multileaf collimator (MLC) gap, and output factors were taken using a PTW 0.125-cc Semiflex ionization chamber, PTW Si-diode, and PTW Microdiamond chamber for field sizes including 6 × 6, 10 × 10, 30 × 30, and 100 × 100 mm Results: All commissioning validation tests satisfied the MPPG 5.b tolerance criteria. The commissioning process took a qualified medical physicist (QMP) and a medical physics resident 1 day to complete. MC dose calculation (2%/1 mm) demonstrated clinically acceptable agreement within 3% of measured dose for E2E tests. In-field PB calculations were within 5%. PB calculated plans showed some improvement with measured values when upgrading the beam model from v4.0 to v4.5. Conclusion: The reference beam model provided an efficient framework for commissioning the Brainlab Elements TPS. Brainlab Elements' MC dose calculation algorithm provides reliable accuracy across clinically relevant heterogenous and small field conditions.

Indexed as

Brainlabcommissioningend-to-end testingSRStreatment planning system

Identifiers

PMID42643383
PMCPMC13503211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.