Evidence map›Paper›PMID 42643375›Full record

ArticleFrontiers in immunology2026

Treatment with saturating dose of conventional anti-CD28 monoclonal antibody well tolerated in pig acute myocardial infarction model.

Anja Stadtmüller, Rebekka Grampp, Giulia Marianantoni, Florian Schnitter, Finja Becker, Könül Nuriyeva, Daniela Langenhorst, Leona Metka, Kira Günther, Lars Wiebusch and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Anja StadtmüllerDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Rebekka GramppDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Giulia MarianantoniInstitute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
Florian SchnitterDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Finja BeckerDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Könül NuriyevaInstitute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
Daniela LangenhorstInstitute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
Leona MetkaInstitute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
Kira GüntherInstitute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
Lars WiebuschDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Kerstin H MairImmunology Unit, Centre of Pathobiology, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Nadine GladowComprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Thomas HerrmannInstitute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
Jan RohrInstitute of Immunodeficiency, Medical Center and Faculty of Medicine, Albert-Ludwigs-University Freiburg, Freiburg, Germany.
Ulrich HofmannDepartment of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Anna Frey *Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
Niklas Beyersdorf *Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

Antibodies, MonoclonalCD28 AntigensMyocardial InfarctionAnimalsDisease Models, AnimalFemaleSwineT-Lymphocytes, RegulatoryAntibodies, MonoclonalCD28 AntigensCD28immunotherapymonoclonal antibodymyocardial infarctionT cells

Identifiers

PMID42643375
PMCPMC13503568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.