ReviewFrontiers in public health2026
Advances in research on the association between global air pollution and atopic dermatitis.
Review in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Escalating global air pollution poses severe threats to public health. Beyond respiratory and cardiovascular damage, air pollutants adversely affect cutaneous health. Atopic dermatitis (AD), a common chronic inflammatory skin disease, has been closely linked to environmental pollutant exposure in recent research, arousing widespread academic concern. Objective: This narrative review aimed to comprehensively summarize current evidence on the correlation between air pollution and AD, and further elaborate the epidemiological features, potential pathogenic mechanisms, as well as targeted prevention and therapeutic strategies for pollution-related AD. Methods: Literature was retrieved from PubMed, Web of Science and CNKI databases covering April 2021 to December 2025, with core keywords related to air pollutants, AD, pathogenesis, exposure and climate change. Following narrative review guidelines, high-quality peer-reviewed studies with an impact factor ≥ 3.0 were included, focusing on cutting-edge evidence regarding air pollutant-AD associations, climatic and geographical disparities, microbiome interactions, and novel therapies. Results: Exposure to particulate matter, nitrogen dioxide, ozone and cigarette smoke significantly increases AD incidence and severity. Key mechanisms include skin barrier damage, skin microbiota dysbiosis, oxidative inflammatory stress, aryl hydrocarbon receptor pathway activation, and epigenetic gene-environment interactions. Urban residents, children, pregnant women and outdoor workers are high-risk populations. Biologics and JAK inhibitors effectively relieve AD symptoms, while antioxidants and medical ozone therapy are promising adjuvant or emerging interventions. Conclusion: Air pollution is a critical modifiable risk factor for AD onset and exacerbation via multi-pathway mechanisms. Integrated prevention, skincare and clinical treatment can reduce AD burden. Current evidence is limited to observational studies, lacking definitive causal verification. Future multicenter prospective cohort studies, standardized novel therapy application and AI-assisted precise management will facilitate systematic AD prevention and control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.