Evidence map›Paper›PMID 42643223›Full record

ArticleiScience2026

Functional and structural characterization of dendritic spine pathology in a mouse model of tauopathy.

Liam M Adsit, Kyle Cekada, Ikuko T Smith

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Liam M AdsitDepartment of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Kyle CekadaNeuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Ikuko T SmithDepartment of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

Funding

Elucidating mechanisms of active dendritic integration in vivoR01NS128079 · NINDS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Ikuko Smith · 2022 to 2026
$1.8M
NINDS NIH HHS R01 NS128079
6 · The paper itself

Abstract

Abnormal deposition of the microtubule-associated protein tau has long been associated with spine loss and neuronal death in neurodegenerative diseases. Elucidating how pathological tau affects synaptic activity

Indexed as

dendritedendritic spineinput mappingneurodegenerative diseasespine lossspine pathologytauopathy

Identifiers

PMID42643223
PMCPMC13503137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.