Evidence map›Paper›PMID 42643203›Full record

ArticleBJUI compass2026

Reducing paralytic ileus after radical cystectomy: The role of advanced haemodynamic monitoring.

Constantin Rieger, Till Löhr, Julian Heidenreich, Anna Rieger, Alexander Mathes, David Sander, Florian A Schmid, Christian Bach, David Pfister, Axel Heidenreich

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Constantin RiegerDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.ORCID https://orcid.org/0009-0000-3993-7974
Till LöhrDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.
Julian HeidenreichDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.
Anna RiegerDepartment of Anesthesiology and Intensive Care Medicine University Hospital of Cologne Cologne Germany.
Alexander MathesDepartment of Anesthesiology and Intensive Care Medicine University Hospital of Cologne Cologne Germany.
David SanderDepartment of Anesthesiology and Intensive Care Medicine University Hospital of Cologne Cologne Germany.
Florian A SchmidDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.
Christian BachDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.
David PfisterDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.ORCID https://orcid.org/0000-0003-3925-9653
Axel HeidenreichDepartment of Urology, Urologic Oncology, Robot-Assisted and Specialized Urologic Surgery University of Cologne Cologne Germany.ORCID https://orcid.org/0000-0002-2511-3664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Despite highly standardized surgical procedures, approximately 20%-30% of patients develop postoperative paralytic ileus following radical cystectomy, representing the highest incidence among abdominopelvic surgeries. The objective of this study was to identify additional predictors of paralytic ileus in a large single-centre cohort. Particular emphasis was placed on expanding the evidence regarding the effectiveness of advanced hemodynamic monitoring using the FloTrac® system. Patients and methods: We retrospectively analysed 383 patients and finally included 296 patients who underwent open or robotic radical cystectomy between 2018 and 2024 at our centre. Of these, 49 patients (16.6%) received intraoperative, minimal invasive FloTrac® monitoring. Perioperative variables were compared between groups, and predictors of paralytic ileus were determined using univariable and multivariable logistic regression analysis. Results: Paralytic ileus occurred in 23.0% of patients overall, with a significantly lower incidence in the FloTrac® group (10.2% vs. 21.3%), corresponding to a 60% relative risk reduction. In multivariable analysis, FloTrac® monitoring (OR 0.37, 95% CI 0.18-0.78, Conclusions: FloTrac® monitoring was independently associated with a markedly lower risk of postoperative paralytic ileus after radical cystectomy. Female sex and higher body weight were identified as additional risk factors. Our findings underscore the potential of FloTrac®-Monitoring to enhance postoperative gastrointestinal recovery for radical cystectomy. Nevertheless, overall surgical complication rates remained comparable.

Indexed as

FloTrac® systemhemodynamic monitoringpostoperative gastrointestinal recoverypostoperative paralytic ileusradical cystectomy

Identifiers

PMID42643203
PMCPMC13503068

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.